Results 131 to 140 of about 655,937 (417)
FEBS Letters, Volume 599, Issue 6, Page 901-911, March 2025.The human Na+/H+ antiporter NHA2 transports Na+ or Li+ in exchange for protons across cell membranes, and its dysfunction results in various pathologies, e.g., fertility disorders, hypertension, or diabetes. This work provides the molecular characterization of interactions of NHA2 with its specific inhibitor phloretin, which can be helpful for the ...
Olga Zimmermannova +3 more
wiley +1 more source
Frontiers in Immunology, 2019 Introduction: The majority of kidneys used for transplantation are retrieved from brain-dead organ donors. In brain death, the irreversible loss of brain functions results in hemodynamic instability, hormonal changes and immunological activation ...
Neeltina M. Jager +10 more
doaj +1 more source
Cancer Medicine, 2020 Background For the advancement of cancer research, the collection of tissue specimens from drug‐resistant tumors after targeted therapy is crucial. Although patients with lung cancer are often provided targeted therapy, post‐therapy specimens are not ...
Theresa A. Boyle +20 more
doaj +1 more source
Estimating the Blood Supply Elasticity: Evidence from a Universal Scale Benefit Scheme [PDF]
arXiv, 2020 I estimate the semi-elasticity of blood donations with respect to a monetary benefit, namely the waiver of user fees when using the National Health Service, in Portugal. Using within-county variation over time in the value of the benefitI estimate both the unconditional elasticity, which captures overall response of the market, and the conditional ...
arxiv
THE “NEW BODY SNATCHERS”: ANALYZING THE EFFECT OF PRESUMED CONSENT ORGAN DONATION LAWS ON PRIVACY, AUTONOMY, AND LIBERTY [PDF]
, 2011 This Note examines, in three parts, presumed consent laws as they pertain to organ donation. Part I discusses presumed consent and explains the salient features of presumed consent laws.
Liddy, Maryellen
core +1 more source
FEBS Letters, Volume 599, Issue 7, Page 1075-1085, April 2025.We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti +2 more
wiley +1 more source
Characterizing Bitcoin donations to open source software on GitHub [PDF]
arXiv, 2019 Web-based hosting services for version control, such as GitHub, have made it easier for people to develop, share, and donate money to software repositories. In this paper, we study the use of Bitcoin to make donations to open source repositories on GitHub.
arxiv
Contract Development In A Matching Market: The Case of Kidney Exchange [PDF]
, 2016 We analyze a new transplant innovation — Advanced Donation, referred to by some as a kidney “gift certificate,” “layaway plan,” or “voucher — as a case study offering insights on both market and contract development. Advanced Donation provides an unusual
Krawiec, Kimberly D. +2 more
core +2 more sources
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
FEBS Letters, Volume 599, Issue 9, Page 1260-1268, May 2025.The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr +4 more
wiley +1 more source
Treating neglected tropical diseases
Community Eye Health Journal, 2013 The name neglected tropical diseases (NTDs) covers a range of diseases that cause disability, early death, and slowed physical and mental development. The first two in entries Table 1 are diseases that cause blindness.
Director: Mectizan Donation Program, Georgia, USA. www.mectizan.org
doaj