Results 171 to 180 of about 655,937 (417)
Immunoregulatory mechanisms of the arachidonic acid pathway in cancer
FEBS Letters, Volume 599, Issue 7, Page 927-951, April 2025.The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine +3 more
wiley +1 more source
Maximum Matchings in Graphs for Allocating Kidney Paired Donation [PDF]
arXiv, 2017 Relatives and friends of an end-stage renal disease patient who offer to donate a kidney are often found to be incompatible with their intended recipients. Kidney paired donation matches one patient and his incompatible donor with another patient and donor in the same situation for an organ exchange.
arxiv
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
Attitudes towards organ donation in Malta in the last decade [PDF]
, 2006 Organ transplantation is possibly one of the few cases when even though the medical professionals have the expertise to carry out transplants of certain organs, and even though a person may have financial resources to cover every possible cost, the ...
Lauri, Mary Anne
core
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Pirates of Charity: Exploring Donation-based Abuses in Social Media Platforms [PDF]
arXivWith the widespread use of social media, organizations, and individuals use these platforms to raise funds and support causes. Unfortunately, this has led to the rise of scammers in soliciting fraudulent donations. In this study, we conduct a large-scale analysis of donation-based scams on social media platforms.
arxiv
Influence of Family Communication on Organ Donation [PDF]
, 2014 Organ donors are in high demand and although many individuals have a favorable attitude toward organ donation, very few are committed to donating. This study aims to examine the impact of mother-daughter relationships and the conversation that stems from
Melino, Arielle
core +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Responsibility and Sustainability, 2020 This study aimed to propose a scale to measure the tendency of an individual to make donations of money/goods in an emerging market. I reviewed the studies regarding donations, obtaining 107 variables from the literature and from the qualitative ...
Emerson Wagner Mainardes
doaj