Results 211 to 220 of about 655,937 (417)

Donation: Gametes

open access: yes, 2015
Gamete donation refers to the different methods of reproductive technologies in which the human sperm, the human oocyte, or both are offered by and obtained from an individual and used in various forms of assisted reproduction procedures and research.
openaire   +2 more sources

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

When a precedent of donation favors defection in the Prisoner's dilemma [PDF]

open access: yes
In this paper we examine the question of wether a collective activity can influence cooperation in a subsequent repeated one shot prisoner's dilemma (PD) game. We conduct two series of experiments.
Garapin, A., Hollard, M., Llerena, D.
core  

Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program

open access: yesNeuropathology (Kyoto. 1993), 2015
T. Beach   +37 more
semanticscholar   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

Analyzing the Usage of Donation Platforms for PyPI Libraries [PDF]

open access: yesarXiv
Software systems rely heavily on open source software (OSS) libraries, which offer benefits but also pose risks. When vulnerabilities arise, the OSS community may struggle to address them due to inactivity or lack of resources. Research highlights the link between OSS maintenance and financial support.
arxiv  

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

open access: yesFEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon   +5 more
wiley   +1 more source

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