Results 251 to 260 of about 577,054 (311)

Kidney Transplantation in Western Balkans: A Regional Blueprint for Access, Capacity, and Equity. [PDF]

Transpl Int
Rista E, Spasovski G, Rebic D, Lausevic M, Radunovic D, Godanci V, Strakosha A, Idrizi A, Saliaj K, Akin EB, Stojanovic J, Ortiz F, Lefaucheur C, Potena L, Chatzixiros E, Azzi J, Mey D.   +16 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Institutional Decoupling in China's Blood Donation Reform: Bridging the Gap Between Policy Intentions and Implementation Realities. [PDF]

Int J Health Policy Manag
Luo R, Lu J.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Organ donation in Saudi Arabia: a profile of public knowledge and behavior from an online survey. [PDF]

Front Public Health
Alobaidi S.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Changes in Organ Donation After Circulatory Death in the United States. [PDF]

JAMA
Husain SA, Motter JD, Stewart D, Levan ML, Bae S, Parent B, Lonze BE, Sommer PM, Gentry SE, Stern JM, Massie AB, Segev DL, Orandi BJ.   +12 more
europepmc   +1 more source

Financing STI testing among men in China: A mixed-methods study of pay-it-forward monetary donations. [PDF]

PLoS One
Liu Y, Zhou K, Li L, Salma G, Fitzpatrick T, Marley G, Zhu Z, Tang W, Tucker JD.   +8 more
europepmc   +1 more source

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Organ Donation

Seminars in Liver Disease, 2009
Liver transplantation expertise has expanded throughout the world to the point where liver transplants are available in most developed countries. In many cases, however, legislation and regulations have not kept pace with the advances in healthcare technology.
Jason, Rhee, Barbara, Kern, Jeffery, Cooper, Richard B, Freeman   +3 more
openaire   +2 more sources