Results 301 to 310 of about 655,937 (417)
Hijacking the BAF complex: the mechanistic interplay of ARID1A and EWS::FLI1 in Ewing sarcoma
Ewing sarcoma is driven by the EWS::FLI1 fusion protein, which disrupts gene expression by hijacking the BAF complex via ARID1A. ARID1A's ability to form biomolecular condensates is crucial for tumor growth, making it a potential therapeutic target. However, targeting these transient condensates is challenging, requiring further research. Ewing sarcoma,
Erich J. Sohn, David S. Libich
wiley +1 more source
Family-Related Motivation and Regret Intensity Among Family Liver Donors by Type of Family Relationship. [PDF]
Lee YS, Koh CK, Yi NJ.
europepmc +1 more source
Preoperative autologous donation: what have we learned? [PDF]
Arthur J. Silvergleid
openalex +1 more source
Is oocyte donation a risk factor for preeclampsia? A systematic review and meta-analysis
A. Blázquez+5 more
semanticscholar +1 more source
Genomic landscape and preclinical models of angiosarcoma
Angiosarcomas are a rare and aggressive cancer with a poor prognosis for patients. The genomic landscape of angiosarcoma can be highly complex and heterogenous; however, recent studies have identified some common features especially within anatomic and molecular subgroups.
Annaleigh Benton+3 more
wiley +1 more source
Alleviating the emotional burden on families during organ donation requests in neurologic patients declared with brain death: the role of timing and circumstances of death. [PDF]
Powla PP, Turaka D, Fakhri F.
europepmc +1 more source
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale+9 more
wiley +1 more source
Evolutionary dynamics of behavioral motivations for cooperation. [PDF]
Su Q, Stewart AJ.
europepmc +1 more source
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu+3 more
wiley +1 more source