Results 201 to 210 of about 92,739 (315)

Re-entry of donors deferred for false-reactive screening tests in Canada: 10 years post implementation. [PDF]

Vox Sang
Wang C, Drews SJ, Bigham M, Goldman M, O'Brien SF.   +4 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Social Representations of Blood Donation: A Qualitative Study in a Referral Hospital in Perú. [PDF]

Health Sci Rep
Fernandez-Bolivar L, Gushiken A.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Enhancing voluntary blood donations: King Fahad Armed Forces Hospital experience with mobile donation campaign. [PDF]

Front Public Health
Bawazir WM, Alzahrani OA, Bukhari AG, Felimban RI, Alsolaimi WA, Algarni NA, Albarqi AA, Alzahrani MS, Sendi NS, Faqih JH, Al-Hindi SM, Alhashmi MH, Al Sadoun H, Kabrah SM, Tounsi WA, Hakami NY.   +15 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Donations

Journal of the Palaeontological Society of India, 1956

doaj   +1 more source

Determinants of iron deficiency among blood donors: a cross-sectional study in a teaching hospital. [PDF]

Sci Rep
Nkansah C, Appiah SK, Osei-Boakye F, Abbam G, Banyeh M, Andoh G, Somuah D, Nyamekye M, Bani SB, Daud S, Derigubah CA, Donkor FN, Quansah Y, Ahmed M, Appiah-Kubi E, Owusu CAA, Dramani B, Selleh PK, Osei-Owusu W, Asare GA, Gyedu D, Chukwurah EF.   +21 more
europepmc   +1 more source

Substitution effects across charitable donations

This paper examines substitution effects across charitable donations, specifically the effect of 2nd collections on 1st collections at Catholic Masses. While 2nd collections increased total donations by 17.8%, 18.4% of 2nd collection donations came from ...
Slonim, Robert, Cairns, Jason
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