Results 151 to 160 of about 74,263 (243)
This study identifies vacuole membrane protein 1 (VMP1) as a critical regulator of intestinal epithelial barrier homeostasis. VMP1 facilitates the recruitment of CORO1C to late endosomes, supporting Retromer‐mediated recycling of the tight junction protein Occludin.
Jiawei Zhao +12 more
wiley +1 more source
MP4 video‘A Stupid Young Man’ was told by Mkha’ ‘gro mthar in A mdo Tibetan. Rta rgyugs, a subdivision of Rka phug Administrative Village, is a farming village located in Khams ra Town, Gcan tsa County Town, Rma lho Tibetan Autonomous Prefecture ...
Rdo rje don 'grub
core
Analysis of the Differentially Expressed Proteins in Donkey Milk in Different Lactation Stages. [PDF]
Zhou M, Huang F, Du X, Liu G, Wang C.
europepmc +1 more source
Hyperosmotic stress drives ferroptosis in corneal epithelium via SIRT1 downregulation. This work demonstrates that SIRT1 activation stabilizes HIF1α, which transcriptionally upregulates GPX4 to inhibit lipid peroxidation and cell death. The identified SIRT1/HIF1α/GPX4 axis reveals a novel defense mechanism and potential therapy for dry eye disease ...
Lili Lian +11 more
wiley +1 more source
The Herdsman and Wolf Cubs [PDF]
MP4 video‘The Herdsman and Wolf Cubs’ was told by Rgyal mtshan in A mdo Tibetan. Rta rgyugs, a subdivision of Rka phug Administrative Village, is a farming village located in Khams ra Town, Gcan tsa County Town, Rma lho Tibetan Autonomous Prefecture,
Rdo rje don 'grub
core
• The activation of the microglial Hcar2 receptor by niacin initiates intracellular signalling that induces metabolic reprogramming. • This metabolic shift is characterized by increased oxidative phosphorylation. Consequently, microglia polarize from a proinflammatory state toward an anti‐inflammatory, reparative phenotype.
Hua Du +7 more
wiley +1 more source
Proximity Labelling Reveals the Compartmental Proteome of Murine Sensory Neurons
ABSTRACT Introduction Understanding the molecular architecture of peripheral sensory neurons is critical as we pursue novel drug targets against pain and neuropathy. Sensory neurons in the dorsal root ganglion (DRG) show extensive compartmentalization; thus, understanding each compartment—from the peripheral to central terminals—is key to this effort ...
Julia R. Sondermann +9 more
wiley +1 more source
Impact of the structural adjustment program on agricultural production and resource use in Egypt: [PDF]
This paper uses an agricultural sector model to evaluate the effects of an ambitious and ongoing policy reform program on agricultural production and resource use in Egypt.
Hazell, P. B. R. +3 more
core
Bioactive peptides (BPs) derived from dietary proteins modulate the gut microbiotametabolism axis by reshaping microbial composition and regulating key metabolites, including short‐chain fatty acids. BPs also enhance intestinal barrier integrity and immune homeostasis, thereby reducing inflammation.
Jiao Li +6 more
wiley +1 more source
Effects of Roughage on the Lipid and Volatile-Organic-Compound Profiles of Donkey Milk. [PDF]
Ren W +11 more
europepmc +1 more source

