Results 41 to 50 of about 14,756 (296)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Purpose of keeping donkeys.

open access: yes, 2022
Purpose of keeping donkeys.
Thinawanga Joseph Mugwabana (14259450)   +2 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

A controlled study on efficacy and egg reappearance period of Ivermectin in donkeys naturally infected with small strongyles

open access: yesHelminthologia, 2020
The aim of the present study was to investigate the efficacy and the egg reappearance period (ERP) of ivermectin (IVM) in donkeys during a 13-week period.
Papini R. A., Orsetti C., Sgorbini M.
doaj   +1 more source

Protection from the elements: a comparative study of hair density, shelter use and heat loss in donkeys, horses and mules [PDF]

open access: yes, 2016
It is widely believed that donkeys are less adapted to wet, temperate climates than horses, often requiring shelter in addition to natural protection and rugs. However, to date there has been no scientific study assessing the shelter needs of donkeys and
Proops, L., Osthaus, B., Burden, F.
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Whole-genome analysis reveals genetic diversity and selection pressure in Sichuan donkey

open access: yesBMC Genomics
Background Sichuan donkeys are small-statured donkeys native to the plateau and mountainous regions of southwestern China. They are well-suited for transportation tasks in mountainous terrain and exhibit remarkable adaptability to the harsh environment ...
Cong Li   +7 more
doaj   +1 more source

Detection of Toxoplasma gondii antibodies in trade donkeys (Equus asinus) at Ganawuri district market, Riyom Local Government area, Plateau State, North Central Nigeria [PDF]

open access: yesInternational Journal of One Health, 2019
Background and Aim: Toxoplasma gondii is a parasite of public health significance due to its possible transmission to humans through ingestion of tissue cysts in raw or undercooked meat or food or water contaminated with oocysts shed by felids and ...
Ishaku Bata Shalangwa   +1 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

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