Results 161 to 170 of about 539,134 (347)

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Does recipient body mass index inform donor selection for allogeneic haematopoietic cell transplantation? [PDF]

open access: yesBr J Haematol, 2022
Abou-Ismail MY   +19 more
europepmc   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Análise dos óbitos de um hospital: busca ativa por potenciais doadores de córneas [Analysis of deaths at a hospital: active search for potential cornea donors] [Análisis de los óbitos de un hospital: búsqueda activa por donadores potenciales de córneas]

open access: yesRevista Enfermagem UERJ, 2012
Estudo descritivo exploratório, com coleta retrospectiva de dados, relativo aos óbitos ocorridos em 2010, com o objetivo de analisar a viabilidade para doação de tecido ocular. Foram analisados 1.047 óbitos.
João Luis Erbs   +3 more
doaj  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

The evaluation of blood donor deferrals at Police General Hospital

open access: yesJournal of Associated Medical Sciences, 2010
Background : Blood donor selection contributes to the safety of both donors and the recipients. The objective of this study was to identify the number and causes of blood donor deferrals. Also the growing trend of the causes of deferrals was studied. The
Surachai Jantavaree
doaj  

Donor selection for lung transplant in Turkey: Is it necessary to wait for an ideal donor? [PDF]

open access: yesTurk Gogus Kalp Damar Cerrahisi Derg, 2021
Vayvada M, Taşçı AE.
europepmc   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

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