Results 11 to 20 of about 539,134 (347)

Turkish Hematologists’ Preferences for Related Donor Selection: Results of a Multicenter Survey [PDF]

Turkish Journal of Hematology
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a widely utilized treatment for various hematological diseases. While selection criteria for unrelated donors are well established, there is a lack of consistency and standardization in ...
Sıdıka Gülkan Özkan, Ali Kimiaei, Ali Hakan Kaya, Mehmet Sezgin Pepeler, Hasan Atilla Özkan, Mutlu Arat   +5 more
doaj   +2 more sources

Donor selection in the modern era. [PDF]

Ann Cardiothorac Surg, 2018
The growing disparity between the supply of donor hearts for transplantation and the demand for such organs has led to liberalization of the criteria for donor heart acceptance over the past few decades. The upper age limit and size restrictions for donor heart acceptance continue to be revised and hearts are being routinely used from donors with left ...
Khush KK.
europepmc   +5 more sources

KIR Donor Selection: Feasibility in Identifying better Donors. [PDF]

Biol Blood Marrow Transplant, 2019
We previously reported that acute myelogenous leukemia (AML) transplants using killer cell immunoglobulin-type receptor (KIR) B haplotype better or best (≥2 B activating gene loci ± Cen B/B) unrelated donors (URDs) yield less relapse and better survival.
Weisdorf D, Cooley S, Wang T, Trachtenberg E, Haagenson MD, Vierra-Green C, Spellman S, Spahn A, Vogel J, Kobusingye H, Fehninger T, Woolfrey A, Devine S, Ross M, Waller EK, Sobecks R, Parham P, Guethlein LA, Marsh SGE, Miller J, participating center writing committee.   +20 more
europepmc   +5 more sources

Framework for rational donor selection in fecal microbiota transplant clinical trials. [PDF]

PLoS ONE, 2019
Early clinical successes are driving enthusiasm for fecal microbiota transplantation (FMT), the transfer of healthy gut bacteria through whole stool, as emerging research is linking the microbiome to many different diseases.
Claire Duvallet, Caroline Zellmer, Pratik Panchal, Shrish Budree, Majdi Osman, Eric J Alm   +5 more
doaj   +2 more sources

Pearls and Pitfalls in Pediatric Kidney Transplantation After 5 Decades

Frontiers in Pediatrics, 2022
Worldwide, over 1,300 pediatric kidney transplantations are performed every year. Since the first transplantation in 1959, healthcare has evolved dramatically. Pre-emptive transplantations with grafts from living donors have become more common. Despite a
Loes Oomen, Charlotte Bootsma-Robroeks, Charlotte Bootsma-Robroeks, Elisabeth Cornelissen, Liesbeth de Wall, Wout Feitz   +5 more
doaj   +1 more source

Humanized Mouse Model as a Novel Approach in the Assessment of Human Allogeneic Responses in Organ Transplantation

Frontiers in Immunology, 2021
The outcome of organ transplantation is largely dictated by selection of a well-matched donor, which results in less chance of graft rejection. An allogeneic immune response is the main immunological barrier for successful organ transplantation.
Ashwin Ajith, Laura L. Mulloy, Md. Abu Musa, Valia Bravo-Egana, Daniel David Horuzsko, Imran Gani, Anatolij Horuzsko   +6 more
doaj   +1 more source

Haplotype Motif-Based Models for KIR-Genotype Informed Selection of Hematopoietic Cell Donors Fail to Predict Outcome of Patients With Myelodysplastic Syndromes or Secondary Acute Myeloid Leukemia

Frontiers in Immunology, 2021
Results from registry studies suggest that harnessing Natural Killer (NK) cell reactivity mediated through Killer cell Immunoglobulin-like Receptors (KIR) could reduce the risk of relapse after allogeneic Hematopoietic Cell Transplantation (HCT). Several
Johannes Schetelig, Johannes Schetelig, Henning Baldauf, Linda Koster, Michelle Kuxhausen, Falk Heidenreich, Falk Heidenreich, Liesbeth C. de Wreede, Liesbeth C. de Wreede, Stephen Spellman, Michel van Gelder, Benedetto Bruno, Francesco Onida, Vinzenz Lange, Carolin Massalski, Victoria Potter, Per Ljungman, Nicolaas Schaap, Patrick Hayden, Stephanie J. Lee, Nicolaus Kröger, Kathy Hsu, Alexander H. Schmidt, Alexander H. Schmidt, Ibrahim Yakoub-Agha, Marie Robin   +25 more
doaj   +1 more source

Estimation of German KIR Allele Group Haplotype Frequencies

Frontiers in Immunology, 2020
The impact of the highly polymorphic Killer-cell immunoglobulin-like receptor (KIR) gene cluster on the outcome of hematopoietic stem cell transplantation (HCST) is subject of current research.
Ute V. Solloch, Daniel Schefzyk, Gesine Schäfer, Carolin Massalski, Maja Kohler, Jens Pruschke, Annett Heidl, Johannes Schetelig, Johannes Schetelig, Alexander H. Schmidt, Alexander H. Schmidt, Vinzenz Lange, Jürgen Sauter   +12 more
doaj   +1 more source

Donor heart selection: the outcome of "unacceptable" donors [PDF]

Journal of Cardiothoracic Surgery, 2007
The decline in the number of suitable donor hearts has led to an increasing interest in the use of previously unacceptable donors. In the United Kingdom, if one centre declines a donor heart on medical grounds it may be offered to other centres. This multi-centre study aimed to evaluate the outcome of recipients of donor hearts considered medically ...
Khasati, Noman H., Machaal, Ali, Barnard, Jim, Yonan, Nizar   +3 more
openaire   +5 more sources

Japanese national survey on declined liver allografts from brain‐dead donors: High decline rate but promising outcomes in allografts with moderate steatosis

Annals of Gastroenterological Surgery, 2023
Aim Liver allografts from brain‐dead donors, which were declined and were eventually not transplanted due to accompanying marginal factors, have never been surveyed in Japan.
Yusuke Takemura, Masahiro Shinoda, Yasushi Hasegawa, Yohei Yamada, Hideaki Obara, Minoru Kitago, Mureo Kasahara, Koji Umeshita, Susumu Eguchi, Yuko Kitagawa, Hideki Ohdan, Hiroto Egawa   +11 more
doaj   +1 more source