Results 301 to 310 of about 835,082 (382)

Identification of a Lipid-Exposed Extrahelical Binding Site for Positive Allosteric Modulators of the Dopamine D₂ Receptor

Herman D. Lim, Damian Bartuzi, Alastair C. Keen, Caroline Rauffenbart, Jacqueline R. Glenn, Steven J. Charlton, Silvia Lovera, Zara A. Sands, Ali Ates, Martyn Wood, Meritxell Canals, Jonathan A. Javitch, Jens Carlsson, J. Robert Lane   +13 more
openalex   +1 more source

Mussel‐Bioinspired Edible Ca2+‐Crosslinked Alginate Hydrogel Electrodes for Glucose Gastrointestinal Monitoring

Advanced Science, EarlyView.
A fully edible soft electrode is engineered from Ca2⁺‐crosslinked alginate integrated with polydopamine, silver nanoparticles, and food‐grade glucose oxidase. The hybrid hydrogel combines ionic and electronic conduction, enabling efficient glucose‐to‐H2O2 conversion and catalytic reduction in simulated intestinal fluid.
Verdiana Marchianò, Claudio Pellegrini, Angelo Tricase, Eleonora Macchia, Andrea Brattelli, Luigi Gentile, Patrizia Nadia Hanieh, Noemi Fiaschini, Antonio Rinaldi, Luisa Torsi, Paolo Bollella   +10 more
wiley   +1 more source

Rat models of lactose intolerance: sexually dimorphic comorbidities with neuropsychiatric disorders modulated by tryptophan hydroxylase and the dopaminergic system. [PDF]

Sci Rep
Galvão MC, Galvão NA, da Silva VSA, Rocha TV, Santos DNL, Carvalho LB, da Silva RAF, Kirsten TB.   +7 more
europepmc   +1 more source

Subsecond dopamine fluctuations do not specify the vigor of ongoing actions [PDF]

Haixin Liu, Riccardo Melani, Marta Maltese, James Taniguchi, Akhila Sankaramanchi, Ruoheng Zeng, Jenna R. Martin, Nicolas X. Tritsch   +7 more
openalex   +1 more source

Smart Nanoparticles Disrupting Energy Supply through Triple Mechanisms to Kill Tumors via Dual Disruption of Mitochondria and Lysosomes

Advanced Science, EarlyView.
This study introduces a biomimetic nanoplatform (MTCA@C) designed for precise cancer therapy. It targets mitochondria to induce dysfunction through photodynamic activation, while concurrently blocking mitophagy via lysosomal alkalinization. The platform further triggers methuosis, resulting in tumor cell death through vacuolization and energy pathway ...
Xiao Xu, Qiqing Huang, Yang Liu, Jinzhuo Liu, Deyi Yang, Yanni Song, Xin Han   +6 more
wiley   +1 more source

Mathematical modeling of dopamine rhythms and timing of dopamine reuptake inhibitors. [PDF]

PLoS Comput Biol
Yao T, Kim R.
europepmc   +1 more source

Intelligent Sensing: The Emerging Integration of Machine Learning and Soft Sensors Based on Hydrogels and Ionogels

Advanced Science, EarlyView.
By integrating with machine learning (ML), hydrogel‐ and ionogel‐based soft sensors are gaining human brain‐like capabilities to perceive, learn, and predict. This review summarizes their advances, focusing on ML‐powered applications such as handwriting/gesture/object/motion/speech recognition, health monitoring, food detection, and beyond.
Wenqing He, Rumin Lin, Suixiu Kong, Mengyi Qiang, Lingqi Huang, Bing Dai, Xi Yao, Lei Su, Xueji Zhang   +8 more
wiley   +1 more source

Unraveling the mysteries of schizophrenia: Insights into prefrontal cortex dysfunction and therapeutic implications. [PDF]

World J Psychiatry
Cheng BF, Liang Y, Wu Q.
europepmc   +1 more source

Ketamine-induced pica behavior as nausea and vomiting involves dopamine and serotonin receptor activation in the area postrema of rats: A comparison with etomidate and pentobarbital

Utaka Sasaki, Masahiro Irifune, Takahiro Kochi, Mukai Tomohiro, Yoki Nakamura, Eiji Imado, Aya Oda, Hisanobu Kamio, Serika Imamura, Kana Oue, Norimitsu Morioka, Yukio Ago   +11 more
openalex   +1 more source

Rod‐Shaped Nanotherapeutics Alleviate Rheumatoid Arthritis by Precisely Disrupting Platelet‐Mediated Pathological Crosstalk via a Morphology‐Dependent Manner

Advanced Science, EarlyView.
Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang, Yuanyi Hua, Xin Wen, Zhumei Liao, Jianheng Ren, Yajun Weng, Qin Wang   +6 more
wiley   +1 more source