Results 61 to 70 of about 3,949,650 (302)

Extensive Variability in Vasoactive Agent Therapy: A Nationwide Survey in Chinese Intensive Care Units

Chinese Medical Journal, 2015
Background: Inconsistencies in the use of the vasoactive agent therapy to treat shock are found in previous studies. A descriptive study was proposed to investigate current use of vasoactive agents for patients with shock in Chinese intensive care ...
Xian-Bo Pei, Peng-Lin Ma, Jian-Guo Li, Zhao-Hui Du, Qing Zhou, Zhang-Hong Lu, Luo Yun, Bo Hu   +7 more
doaj   +1 more source

Aripiprazole, a novel antipsychotic agent: Dopamine D2 receptor partial agonist

The Journal of Medical Investigation, 2005
It is obvious that DA is an important neurotransmitter in vivo. It is involved in a variety of physiological processes such as mental processes, motor function and hormone regulation. In this context, it is quite understandable that a DA D2 receptor antagonist that inhibits the DA D2 receptor regardless of the state of activity of dopaminergic ...
Hirose, Tsuyoshi, Kikuchi, Tetsuro
openaire   +3 more sources

Study of a Novel Bi‐Layered Thermoplastic Polyurethane Patch for Congenital Diaphragmatic Hernia

Advanced Materials Interfaces, EarlyView.
Large congenital diaphragmatic hernia remains a challenge due to the poor compatibility of current prostheses. To tackle this problem, a bilayer thermoplastic polyurethane patch with tunable mechanical properties is engineered, whose fibrous side supports rapid fibroblast and myoblast colonization, while the smooth film limits adhesions.
Guillaume Leks, Julie Favre, Manon Zislin, Rodolphe Migneret, Jordana Hirtzel, Vincent Ball, Cendrine Seguin, Anne Hebraud, Emeline Lobry, Guy Schlatter, Nadia Bahlouli, Hamdi Jmal, Benoît Frisch, Sylvie Fournel, Isabelle Talon   +14 more
wiley   +1 more source

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

Blockade of Intranigral and Systemic D3 Receptors Stimulates Motor Activity in the Rat Promoting a Reciprocal Interaction among Glutamate, Dopamine, and GABA

Biomolecules, 2019
In vivo activation of dopamine D3 receptors (D3Rs) depresses motor activity. D3Rs are widely expressed in subthalamic, striatal, and dendritic dopaminergic inputs into the substantia nigra pars reticulata (SNr).
Marina Rodríguez-Sánchez, Rodrigo Erick Escartín-Pérez, Gerardo Leyva-Gómez, José Arturo Avalos-Fuentes, Francisco Javier Paz-Bermúdez, Santiago Iván Loya-López, Jorge Aceves, David Erlij, Hernán Cortés, Benjamín Florán   +9 more
doaj   +1 more source

Hydrogel‐Based Functional Materials: Classifications, Properties, and Applications

Advanced Materials Technologies, EarlyView.
Conductive hydrogels have emerged as promising materials for smart wearable devices due to their outstanding flexibility, multifunctionality, and biocompatibility. This review systematically summarizes recent progress in their design strategies, focusing on monomer systems and conductive components, and highlights key multifunctional properties such as
Zeyu Zhang, Zao Cheng, Patrizio Raffa
wiley   +1 more source

Mapping of Physiological Signals From Wireless Battery‐Free Implants With Plane‐Wave Ultrasound Imaging

Advanced Materials Technologies, EarlyView.
Combined approach of electromagnetic (Power) and ultrasound (data harvesting) waves is proposed to address the miniaturized ultrasonic implants. Electromagnetic waves trigger the piezoelectric element to generate the acoustic pulse which is modulated by the variations in the sensor's impedance.
Anam Bhatti, Hugo Guillot, Ouafae Firdaouissi, Mohammed Irar, Lionel Rousseau, Clément Hébert, Maxime Lafond   +6 more
wiley   +1 more source

Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease

Neurobiology of Disease, 2016
To investigate whether the endogenous neuropeptide nociceptin/orphanin FQ (N/OFQ) contributes to the death of dopamine neurons in Parkinson's disease, we undertook a genetic and a pharmacological approach using NOP receptor knockout (NOP−/−) mice, and ...
Ludovico Arcuri, Riccardo Viaro, Simone Bido, Francesco Longo, Mariangela Calcagno, Pierre-Olivier Fernagut, Nurulain T. Zaveri, Girolamo Calò, Erwan Bezard, Michele Morari   +9 more
doaj   +1 more source

Magnetic Field Driven Microrobot Based on Hydrogels

Advanced Robotics Research, EarlyView.
Hydrogel‐based magnetic microrobots synergize remote magnetic control with the biocompatibility of flexible hydrogels, emerging as promising tools for minimally invasive biomedicine. This enables remotely controllable, untethered navigation within complex biological microenvironments.
Juncai Song, Yubing Guo
wiley   +1 more source

Altered dopamine ontogeny in the developmentally vitamin D deficient rat and its relevance to schizophrenia

Frontiers in Cellular Neuroscience, 2013
Schizophrenia is a heterogeneous group of disorders with unknown aetiology. Although abnormalities in multiple neurotransmitter systems have been linked to schizophrenia, alterations in dopamine neurotransmission remain central to the treatment of this ...
James P. Kesby, Xiaoying eCui, Thomas H.J. Burne, Thomas H.J. Burne, Darryl Wakter Eyles, Darryl Wakter Eyles   +5 more
doaj   +1 more source