Results 321 to 330 of about 589,499 (392)

Translating physiology of the arterial chemoreflex into novel therapeutic interventions targeting carotid bodies in cardiometabolic disorders

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The carotid body develops aberrant high activity in chronic heart failure, resistant hypertension, obstructive sleep apnoea (OSA) and diabetes. Hyperactivity of the carotid body leads to both high tonicity and increased sensitivity of the arterial chemoreflex with resultant sympathoexcitation.
Tymoteusz Żera   +7 more
wiley   +1 more source

Oxygen chemoreceptor inhibition by dopamine D2 receptors in isolated zebrafish gills

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Transgenic Tg(elavl3:GCaMP6s) zebrafish, which express an endogenous calcium reporter in gill oxygen chemoreceptors and nerve terminals, were used to explore the role of dopamine in hypoxia signalling. We discovered that dopamine via presynaptic dopamine D2 receptors (D2R) provides a feedback mechanism attenuating the ...
Maddison Reed, Michael G. Jonz
wiley   +1 more source

Sodium Oxybate‐Treated Familial Myoclonus‐Dystonia Syndrome Due to Novel SGCE Variant

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 5, May 2025.
ABSTRACT Myoclonus‐dystonia syndrome (MDS, OMIM #159900) is an autosomal‐dominant movement disorder caused by heterozygous variants in the epsilon sarcoglycan gene (SGCE) and characterized by a combination of myoclonic jerks, dystonia, and psychiatric comorbidities.
Malak Ali Alghamdi   +10 more
wiley   +1 more source

Medication equivalent dose program in R

open access: yes
Psychiatry and Clinical Neurosciences, EarlyView.
Shinsuke Koike   +3 more
wiley   +1 more source

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