Results 131 to 140 of about 52,918 (218)

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

eFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie, Wei Fang, Zean Song, Zhang Yu, Ying Zhu, Shaoping Liu   +5 more
wiley   +1 more source

Filamin A phosphorylation at S2152: a molecular switch fueling cancer and neurodegeneration. [PDF]

Cell Commun Signal
Burns LH, Romero A.
europepmc   +1 more source

Cilia in Nervous System Development, Function, and Disease

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley   +1 more source

Syntaxin1A in synaptopathies: From molecular mechanisms to therapeutic implications in neurological disorders (Review). [PDF]

Biomed Rep
Huang Y, Xi J, Su B, Wang P, Xie C, Yuan Y, Yin X, Bao B.   +7 more
europepmc   +1 more source

A Roadmap for Breeding Sweet Tomatoes

Modern Agriculture, Volume 4, Issue 1, June 2026.
This graphical abstract outlines four breeding strategies for enhancing sugar content and sweetness in tomato fruits: (1) Identification of key genes and functional variant loci regulating fruit sugar accumulation through systematic germplasm collection, genome‐wide association studies (GWAS), map‐based cloning, and reverse genetics approaches.
Jie Chen, Hongjun Lyu, Jinzhe Zhang
wiley   +1 more source

When Pathways Converge: Iron, Lipid Peroxidation, and α-Synuclein in Ferroptosis-Driven Dopaminergic Neurodegeneration. [PDF]

J Neurochem
Sperlich CL, Stockwell BR, Farina M.
europepmc   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Membrane Dysfunction as a Central Mechanism in LRRK2-Associated Parkinson's Disease: Comparative Analysis of G2019S and I1371V Variants. [PDF]

Cells
Singh K, Banerjee R, Potdar C, Shaw A, Rakshith R, Kamble N, Holla V, Yadav R, Pal PK, Datta I.   +9 more
europepmc   +1 more source

Permeabilized cells [PDF]

, 1991
Gratzl, Manfred, Wilschut, J.
core  

Japanese Cohort Study and Meta‐Analysis Demonstrate Significant Association Between Serotonin Transporter‐Linked Polymorphic Region and Schizophrenia

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
This study demonstrates a significant association between the 5‐HTTLPR polymorphism and schizophrenia risk. The short allele was significantly overrepresented in patients (OR = 1.39, p = 0.007), suggesting a potential contribution to schizophrenia risk.
Masao Miyachi, Toshiyuki Shirai, Shohei Okada, Kiriko Minami, Ryo Tsukamoto, Kentaro Mouri, Satoshi Okazaki, Ikuo Otsuka, Akitoyo Hishimoto   +8 more
wiley   +1 more source