Results 41 to 50 of about 24,200 (214)

Membrane partitioning by Flotillin-1 facilitates amphetamine-induced dopamine transporter activity [PDF]

open access: yes, 2017
Cellular membranes were once considered static and passive structures, but are now appreciated as a fluidic and dynamic assembly of macromolecules that play an active role in cellular function.
Fong, Wendy Mei
core   +2 more sources

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

open access: yesAdvanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan   +11 more
wiley   +1 more source

In Vivo Electrochemical Monitoring of Safinamide Pharmacokinetics in the Brain Explores Its Correlation With Vision‐Related Neuronal Activity

open access: yesAdvanced Science, EarlyView.
An electrochemical platform based on differential pulse amperometry enables real‐time, selective tracking of safinamide pharmacokinetics in the living brain with high spatiotemporal resolution. When integrated with electrophysiology, this approach reveals that drug‐induced suppression of vision‐related neuronal activity provides mechanistic insight ...
Xiaoke Nan   +9 more
wiley   +1 more source

Studies on ion movement in malpighian tubules of locusta migratoria l. with particular reference to electrical events [PDF]

open access: yes, 1987
Intracellular microelectrodes have been used in conjunction with ion substitution, and agonists and inhibitors of known transport processes to investigate the mechanisms whereby ions cross the basal and apical cell membranes of the Malpighian tubules of ...
Baldrick, Paul
core  

A Wireless 3D Magneto‐Mechanical Stimulation Platform Drives In Situ Chondrogenic Commitment of Endogenous MSCs

open access: yesAdvanced Science, EarlyView.
An intracellular magneto‐mechanical platform utilizing MSC‐targeted nanomotors is developed. After intra‐articular delivery, these nanomotors target endogenous BMSCs and are actuated within lysosomes to execute trans‐planar rotational‐bouncing motions under a rotating‐fluctuating 3D magnetic field, generating amplified mechanical stimulation.
Zhenguang Li   +7 more
wiley   +1 more source

Regulación de receptores de neurotransmisores y neuromoduladores por proteínas estructurales [PDF]

open access: yes, 2003
[cat] Los receptores acoplados a proteína G o de siete dominios transmembrana (GPCRs o 7TMR) constituyen la mayor superfamilia de receptores de membrana involucrados en la transducción de una señal extracelular al interior de la célula.
Burgueño Hurtado, Javier
core  

"In vitro" study of the mode of action of antidepressants in cell culture models : comparison of the effects of "Hypericum perforatum L." extracts and classical synthetic compounds on the [beta]-adrenergic signal pathway [PDF]

open access: yes, 2005
The clinical effectiveness of the plant extract of Hypericum perforatum L. in treating mild to moderate depression is well established. The extract shows a more favourable side effect profile than other antidepressant drugs, like tricyclics and selective
Wirz, Adrian
core   +1 more source

Chronic Disease Monitoring Using Advanced Compliant Materials for Bioelectronics

open access: yesAdvanced Electronic Materials, EarlyView.
Compliant bioelectronic systems enable continuous monitoring of chronic disease through soft, stretchable materials and tissue‐conformal designs that support stable electrophysiological, mechanical, and biochemical sensing. Integration of diverse sensing modalities with thoughtful material selection, device architectures, and advanced fabrication ...
Han Kim   +7 more
wiley   +1 more source

Biochemical, cytochemical localization and physiological studies on Malpighian tubules of Locusta Migratoria L. [PDF]

open access: yes, 1997
Specific inhibitors of protein kinase A (PKA), Rp-cAMP, protein kinase C (PKC), chelerythrine and staurosporine, and protein phosphatase 1 and 2A okadaic acid, inhibited fluid secretion whilst corpora cardiaca (CC) extract and cAMP were found to ...
Ali Al-Fifi, Zarrag, Al-Fifi, Z.I.A.
core  

Drp1 ablation in the adult mouse forebrain [PDF]

open access: yes, 2014
Due to their high energy demand, their highly polarized nature and the sheer length of their processes, neurons - more than any other cell type - depend on a well-balanced dynamic mitochondrial network.
Oettinghaus, Bjorn
core   +1 more source

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