Results 71 to 80 of about 24,200 (214)
Monoamine oxidase in neuronal cell death [PDF]
, 2008 Monoamine oxidase (MAO) is an oxidative enzyme that deaminates a variety of amine substrates, including the neurotransmitter dopamine. The enzymatic reaction requires molecular oxygen and produces hydrogen peroxide as a by-product.
Fitzgerald, J
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Investigation of the interaction of bile acids with the dopamine transporter DAT [PDF]
, 2022 Bile acids (BAs) are cholesterol derivatives primarily involved in dietary fat absorption; new evidence supports a possible additional role in regulating the reward system.
Daniele Zanella +4 more
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Implantable electrochemical sensors for continuous blood monitoring
FlexMat, EarlyView.Implantable electrochemical sensors enable direct, in situ, and continuous blood monitoring, shifting diagnosis from population‐based averages to dynamic, individualized analysis. This review systematically examines the influence of the unique blood properties on sensor design.
Kuangyi Zou +3 more
wiley +1 more source
Body‐integrated photonic biosensors: Illuminating the path to active healthcare
FlexMat, EarlyView.Body‐integrated photonic biosensors are promising tools for active healthcare. These optical devices can be worn, implanted, or swallowed to monitor health signals continuously. This review introduces key sensing modalities, including fluorescence, colorimetry, SPR, LSPR, SERS, and light‐modulating materials.
Jiayue Gu +10 more
wiley +1 more source
Pharmacological therapies for monogenic obesity caused by MC4R dysfunction [PDF]
, 2010 PhDMutations in the melanocortin-4 receptor (MC4R) are the most common cause of monogenic obesity. The majority of MC4R mutations are predicted to cause the receptor to aberrantly fold.
Gooljar, Sakina B
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International Journal of Cancer, EarlyView.ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari +10 more
wiley +1 more source
Metal‐dependent regulated cell death: Molecular architecture and translational frontiers
iMeta, EarlyView.Intracellular metal dyshomeostasis orchestrates distinct regulated cell death programs, including iron‐driven ferroptosis, copper‐mediated cuproptosis, calcicoptosis, newly designated zincoptosis, mnoptosis, and coptosis. This review systematically delineates their molecular architectures—spanning from Sorafenib‐induced lipid peroxidation and ...
Haoliang Hu +20 more
wiley +1 more source
“ Obesity serum factors affect human platelets SERT: we need a cellular model to investigate “ [PDF]
, 2010 Amongst molecules active in modulating 5-HT transmission, SERT exerts a main function by promoting 5-HT clearance and re-uptake into the pre-synaptic terminal, therefore controlling either the duration and extent of the transmitter action at specific ...
FABBRINI, LAURA
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iMeta, EarlyView.Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni +26 more
wiley +1 more source
Development of microarray techniques for the study of gene expression in the European eel (Anguilla anguilla) during silvering and migration to seawater [PDF]
, 2008 Electronic version does not contain associated previously published materialThe European eel, Anguilla anguilla, has a complex life-cycle involving migrations between the Sargasso Sea and the river systems of Europe and North Africa. The requirement to
McWilliam, Iain Stuart
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