Results 151 to 160 of about 128,837 (259)

Striatal neurones expressing D1 dopamine receptors modulate consciousness in sevoflurane but not propofol anaesthesia in mice. [PDF]

Br J Anaesth
Zhou K, Hou ZJ, Jiang XL, Xiao YJ, Zhang LC, Xu W, Xiong B, Qu WM, Huang YG, Huang ZL, Wang L.   +10 more
europepmc   +1 more source

Effort-based decision making in response to high-dose androgens: role of dopamine receptors. [PDF]

Behav Pharmacol, 2022
Donovan A, Wood RI.
europepmc   +1 more source

Clozapine:norclozapine ratio as a marker of metabolic risk and therapeutic response and effect of valproate on clozapine levels

British Journal of Clinical Pharmacology, EarlyView.
Aims Clozapine is the most effective antipsychotic in treatment‐resistant schizophrenia. Clozapine causes weight gain and increased diabetes risk. The role of its metabolite norclozapine and clozapine:norclozapine ratio (CLZ/NCLZ) in metabolic effects has been debated.
Susanna Maria Rask, Miina Lamminmäki, Olli Kampman, Mari Hämäläinen, Eeva Moilanen, Niko Seppälä, Anssi Solismaa   +6 more
wiley   +1 more source

Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors. [PDF]

Nat Neurosci
Enriquez-Traba J, Arenivar M, Yarur-Castillo HE, Noh C, Flores RJ, Weil T, Roy S, Usdin TB, LaGamma CT, Wang H, Tsai VS, Kerspern D, Moritz AE, Sibley DR, Lutas A, Moratalla R, Freyberg Z, Tejeda HA.   +17 more
europepmc   +1 more source

Real time in vivo efficacy monitoring of desialylation and perforation enhanced immunotherapy of cancer

BMEMat, EarlyView.
A multifunctional nanomedicine is designed to engineer NK cells for enhanced cancer immunotherapy through perforation and desialylation, enabling real‐time monitoring of ATP and GrB levels for precise efficacy assessment. Abstract Efficient enhanced NK cell therapy is of critical importance in the immune treatment of cancer.
Yuanjiao Yang, Yuru Wang, Xuemei Li, Chaoyi Yang, Yuhui Yang, Yanyun Fang, Lin Ding, Yunlong Chen, Huangxian Ju   +8 more
wiley   +1 more source

Dopamine receptors D1, D2, and D4 modulate electrical synapses and excitability in the thalamic reticular nucleus. [PDF]

J Neurophysiol
Vaughn MJ, Yellamelli N, Burger RM, Haas JS.   +3 more
europepmc   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

D1-like dopamine receptors promote B-cell differentiation in systemic lupus erythematosus. [PDF]

Cell Commun Signal
Xiang Z, Wu F, He Z, Tan F, Hu H, Zou C, Yi P, Liu W, Yang M.   +8 more
europepmc   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Pharmacological Modulation of Dopamine Receptors Reveals Distinct Brain-Wide Networks Associated with Learning and Motivation in Nonhuman Primates. [PDF]

J Neurosci
Fujimoto A, Elorette C, Fujimoto SH, Fleysher L, Rudebeck PH, Russ BE.   +5 more
europepmc   +1 more source