Results 141 to 150 of about 177,862 (267)

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Functional neuroanatomy of dopaminergic arousal systems: implications for the wake-promoting effect of psychostimulants, with particular reference to modafinil. [PDF]

Front Neuroanat
Szabadi E.
europepmc   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source

The Impact of a Rosemary Containing Drink on Cognition and Mood: The Role of Eye Blink Dynamics. [PDF]

NeuroSci
Riby LM, Kardzhieva D, Fenwick S, Fowler S, Moss M.   +4 more
europepmc   +1 more source

A Sequential Intrastriatal Dopaminergic Graft Strategy in the Rodent Model for Parkinson's Disease: Implications for Graft Survival and Targeting [PDF]

, 2002
K. Adam Baker, M. B. Purdy, D. Sadi, Karim Mukhida, I. Méndez   +4 more
openalex   +1 more source

Neurobiological correlates of obsessive‐compulsive disorder (OCD): A narrative review

Ibrain, EarlyView.
Obsessive‐compulsive disorder (OCD) is a common and disabling, as well as underdiagnosed, neuropsychiatric condition characterized by involuntary and unwanted obsessions and/or compulsions often accompanied by states of severe anxiety, distress and shame, as well as other comorbid disorders. Despite the extensive literature available to date, only some
Giulio Perrotta, Anna Sara Liberati
wiley   +1 more source

Reduced striatal dopamine transmission as a transdiagnostic substrate of psychomotor retardation. [PDF]

Brain
Leong IL, Ng TH, Sen K, Burchill E, Costello H, Badenoch JB, Coebergh J, McCutcheon RA, Nair A, Browning M, Huys QJM, Lewis G, Lees A, David AS, Rogers JP.   +14 more
europepmc   +1 more source

High-fat diet exacerbates 1-Bromopropane-induced loss of dopaminergic neurons in the substantia nigra of mice through mitochondrial damage associated necroptotic pathway

Mingxue Song, Yalong Qiang, Shuai Wang, Shan Shan, Liwen Zhang, Caipei Liu, Fuyong Song, Xiulan Zhao   +7 more
openalex   +1 more source

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

iMetaOmics, EarlyView.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

Loss of Thy1 in Cortico-Striatal Pathways Alters Response to Dopamine and Gabapentin. [PDF]

ASN Neuro
Goletiani C, McEchron MD, Neely E, Connor JR.   +3 more
europepmc   +1 more source