Results 321 to 330 of about 240,256 (373)

The Effect of Multimodal Exercise on the Levels of BDNF and GDNF in Patients with Parkinson's Disease. [PDF]

Int J Prev Med
Naser AA, Dehkordi KJ, Radhi MN, Taghian F, Chitsaz A.   +4 more
europepmc   +1 more source

Lysosomal TPC2 channels disrupt Ca2+ entry and dopaminergic function in models of LRRK2-Parkinson's disease. [PDF]

J Cell Biol
Gregori M, Pereira GJS, Allen R, West N, Chau KY, Cai X, Bostock MP, Bolsover SR, Keller M, Lee CY, Lei SH, Harvey K, Bracher F, Grimm C, Hasan G, Gegg ME, Schapira AHV, Sweeney ST, Patel S.   +18 more
europepmc   +1 more source

FLP-15 functions through the GPCR NPR-3 to regulate local and global search behaviours inCaenorhabditis elegans

Bhat US, Surendran S, H S, Liu J, Xu Y, Tasnim N, Bhardwaj A, Scholz M, Babu K.   +8 more
europepmc   +1 more source

A new dopaminergic prodrug [PDF]

Nature, 1978
THE clinical treatment of parkinsonism with the dopamine (DA) precursor L-dopa has certain drawbacks1 and there are relatively few drugs which directly stimulate DA receptors (although there are many which block them, such as the neuroleptics). There is thus great industrial, academic and clinical interest in the development of new DA-receptor ...
Alan S. Horn, Hans Rollema, D. de Kaste, Cor J. Grol, Durk Dijkstra, Bhc Westerink, M.G.P. Feenstra, A. Westerbrink   +7 more
openaire   +3 more sources

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GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons.

Science, 1993
A potent neurotrophic factor that enhances survival of midbrain dopaminergic neurons was purified and cloned. Glial cell line-derived neurotrophic factor (GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the ...
L.-F. H. Lin, D. Doherty, J. Lile, S. Bektesh, F. Collins   +4 more
semanticscholar   +1 more source

Dopaminergic and non-dopaminergic circling activity of mice

Neuroscience, 1979
Abstract Male ICR albino mice kept in a closed space tend to rotate and have a preferred direction of rotation, which is more often to the left (65%) than to the right (35%). This circling asymmetry was measured with a rotometer in a group of animals following administration of various drugs.
A.D. Korczyn, Y. Eshel
openaire   +3 more sources

Dopaminergic defect in hypertension [PDF]

Pediatric Nephrology, 1993
Reverse genetics and the candidate gene approach have been utilized to identify the genetic defect(s) in hypertension. We have proposed the dopamine receptor gene as one candidate in the pathogenesis of hypertension. Because some forms of hypertension are sodium dependent or aggravated by sodium loading and because dopamine is important in aiding the ...
Robin A. Felder, Pedro A. Jose, Gilbert M. Eisner   +2 more
openaire   +2 more sources

Flavonoids as dopaminergic neuromodulators

Molecular Nutrition & Food Research, 2016
ScopeThe present study aimed to characterize and evaluate flavonoids effects on organic cation uptake in neuronal cells.Methods and resultsUptake experiments were conducted using radiolabeled methyl‐4‐phenylpyridinuim ([3H]‐MPP+), in human neuronal dopaminergic cells, SH‐SY5Y.
Meireles, M., Moura, E., Vieira-Coelho, M.A., Santos-Buelga, C., Gonzalez-Manzano, S., Dueñas, M., Mateus, N., Faria, Ana, Calhau, C.   +8 more
openaire   +4 more sources