Results 151 to 160 of about 449,448 (310)

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia   +16 more
wiley   +1 more source

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

open access: yesHepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid   +20 more
wiley   +1 more source

The development and validation of a new diagnostic sonographic enthesitis score for psoriatic arthritis: Diagnostic Ultrasound Enthesitis Tool (DUET)

open access: yesArthritis &Rheumatology, Accepted Article.
Objective The Diagnostic Ultrasound Enthesitis Tool (DUET) study aimed to develop and validate a new sonographic scoring system for enthesitis to aid PsA diagnosis. Methods We prospectively enrolled patients with early PsA, psoriasis without arthritis (PsO), and non‐inflammatory musculoskeletal symptoms as controls (CTL) from 17 centers. A standardized
Lihi Eder   +27 more
wiley   +1 more source

EBHIS Local Volume Galaxy Hi Survey (LVGHIS)

open access: yesAstronomische Nachrichten, EarlyView.
ABSTRACT Here, we present the “Local Volume Galaxy Hi Survey” (LVGHIS). It is based on the first data release of the Milky Way portion of the Effelsberg Bonn Hi‐Survey (EBHIS). We homogeneously measured the mass and dynamics of the local volume galaxies within the radial velocity limit of |vLSR|≤600kms−1$$ \mid {v}_{\mathrm{LSR}}\mid \le 600\kern0.6em \
V. A. Schulz   +3 more
wiley   +1 more source

Induction Temperature and Feeding Profile Shape the Partitioning Between Soluble Product and Inclusion Body Formation in Escherichia coli

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Inclusion body (IB) processes yielding the recombinant product only as IBs are long‐established in the biopharmaceutical industry. Yet, for recombinant proteins that accumulate both IBs and soluble fraction depending on the selected upstream processing (USP) strategy, the influence of process parameters on the partitioning between both forms ...
Mohamed Elshazly   +7 more
wiley   +1 more source

Diagnostic and morphometric studies on dilated cardiomyopathy in mixed breed cats

open access: yesBulgarian Journal of Veterinary Medicine
Feline dilated cardiomyopathy (DCM) is a rare condition, with idiopathic etiology, non-specific clini-cal manifestations, and sudden death. The DCM diagnostic protocol was studied in mixed-breed cats along with the morphometric study of their hearts ...
R. T. Reem   +3 more
doaj   +1 more source

Tensions of Sustainability Logics: Performance of a Company Utilizing a Sustainable Business Model

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT In recent years, companies have used sustainable business models to gain a competitive advantage. However, there are tensions due to the inconsistency between social, environmental, and economic logic in sustainable business models, making it difficult for companies to change. To understand the existing tensions and interactions between logics,
Ann‐Kristin Thienemann
wiley   +1 more source

Iliofemoral Deep Vein Thrombosis Despite Repeatedly Negative D-Dimer Results. [PDF]

open access: yesClin Case Rep
Randrianarisoa RMF   +6 more
europepmc   +1 more source

Doppler and color doppler ultrasound for the evaluation of blood flow in medical diagnostics

open access: yes
openLa tesi consiste in un'analisi dei principi fisici e delle modalità operative dell'ecografia doppler e del colour doppler. In particolare tratta dell'applicazione di queste tecnologie in diagnostica medica per lo studio del flusso ematico, con un ...
BOCCIA, ANNA MARIA
core  

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