Results 161 to 170 of about 69,651 (314)

The Mitochondria‐Targeted Peptide Therapeutic Elamipretide Improves Cardiac and Skeletal Muscle Function During Aging Without Detectable Changes in Tissue Epigenetic or Transcriptomic Age

open access: yesAging Cell, EarlyView.
The effects of the mitochondria‐targeted peptide therapeutic elamipretide on age‐related muscle function were compared with its effects on molecular biomarkers of aging. It was found that elamipretide treatment partially reverses age‐related cardiac dysfunction and skeletal muscle weakness in mice without significantly affecting muscle epigenetic or ...
Wayne Mitchell   +5 more
wiley   +1 more source

PULMONARY HYPERTENSION IN PATIENTS WITH VIRAL CIRRHOSIS

open access: yesActa Biomedica Scientifica, 2014
To study the peculiarities of the formation of pulmonary hypertension in patients with viral cirrhosis we carried out tissue Doppler echocardiography, Doppler echocardiography, duplex vascular scanning, research of respiratory function in patients with ...
M. V. Chistyakova   +2 more
doaj  

Preprocedural transthoracic Doppler echocardiography to identify stenosis associated with increased coronary flow after revascularisation. [PDF]

open access: yesSci Rep, 2022
Yamaguchi M   +15 more
europepmc   +1 more source

Diabetes Advances Cardiomyocyte Senescence Through Interfering Rnd3 Expression and Function

open access: yesAging Cell, EarlyView.
Diabetes‐induced upregulation of miR‐103a‐3p suppresses Rnd3 expression in cardiomyocytes, thereby promoting the senescence‐associated secretory phenotype (SASP) through activation of the STAT3 signaling pathway, mediated by UPS‐induced degradation of p‐STAT3.
Linxu Wu   +16 more
wiley   +1 more source

Development of tissue Doppler-derived predictors of hemodynamically significant patent ductus arteriosus and the ability to incorporate it in targeted neonatal echocardiography protocol

open access: yesJournal of the Saudi Heart Association, 2019
Background: Hemodynamically significant (HS) patent ductus arteriosus (PDA) is a significant cause of mortality in preterm neonates. Early detection of HS PDA and pre-symptomatic closure may help in avoiding complications.
Sonia El-Saiedi   +6 more
doaj  

Self-supervised learning assisted diagnosis for mitral regurgitation severity classification based on color Doppler echocardiography. [PDF]

open access: yesAnn Transl Med, 2022
Yang F   +10 more
europepmc   +1 more source

Measurement and interpretation of central venous pressure: a narrative review

open access: yesAnaesthesia, EarlyView.
Summary Introduction Central venous pressure has been a key component of haemodynamic monitoring for several decades, but its clinical utility is still debated. While central venous pressure has been used traditionally to assess intravascular volume status and fluid responsiveness, mounting evidence suggests that its absolute value alone is an ...
Patryck Lloyd‐Donald   +3 more
wiley   +1 more source

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