Results 211 to 220 of about 596,703 (340)
Hevin Promotes Aging‐Related Cardiac Dysfunction via Facilitating Cardiac Inflammation in Male Mice
Hevin released by iWAT into circulation stimulates cardiac macrophages through TLR4, inducing their polarization and CCL5 secretion, leading to worsened cardiac dysfunction and subsequent recruitment of additional inflammatory cells for pro‐inflammatory factor release.
Shi‐Yu Huang +4 more
wiley +1 more source
Valvular regurgitation by color doppler echocardiography
André Schmidt +4 more
doaj +1 more source
Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging
Mouse models revealed age‐associated increased circumferential stiffness of the proximal pulmonary artery that was associated with reorientation of collagen and decreased function of the lung and right ventricle. Age‐related transcriptional changes were indicative of senescence, ECM turnover, TGFβ signaling, and altered intercellular signaling among ...
Ruben De Man +22 more
wiley +1 more source
+6 more sources
Quantification of valvular regurgitation by transthoracic 3D high pulse repetition frequency Doppler echocardiography. [PDF]
Berg EAR +9 more
europepmc +1 more source
The Role of Exercise Doppler Echocardiography to Unmask Pulmonary Arterial Hypertension in Selected Patients with Systemic Sclerosis and Equivocal Baseline Echocardiographic Values for Pulmonary Hypertension. [PDF]
Rallidis LS +9 more
europepmc +1 more source
An age‐adapted therapy pairs δ‐Amyrenone, a CBX7 inhibitor, with an alginate hydrogel (CSAδ) to rescue infarcted elderly hearts. CSAδ disrupts CBX7–ATP7A liquid–liquid phase separation, restores ATP7A trafficking and copper efflux, suppresses cuproptosis, supplies oxygen, scavenges ROS, promotes M2 polarization, supports angiogenesis, and enhances ...
Jun Liu +11 more
wiley +1 more source

