Results 211 to 220 of about 108,432 (352)

Stabilisation of PRCP by deubiquitinase‐targeting chimera (DUBTAC) to replenish autophagy for ameliorating pathological cardiac hypertrophy

British Journal of Pharmacology, EarlyView.
Background and Purpose Autophagy is essential for cellular homeostasis, and its impairment contributes to cardiac hypertrophy. Modulating autophagy has shown potential in treating pathological hypertrophy. Prolylcarboxypeptidase (PRCP), a lysosomal enzyme that hydrolyzes angiotensin II to Ang1‐7, has an unclear role in cardiac autophagy and hypertrophy.
Fangchao Zhou, Jun Xia, Yingjuan Liu, Wenqi He, Hongyuan Zhang, Bernard D. Keavney, Min Zi, Binh Y. Nguyen, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Susanne S. Hille, Elizabeth J. Cartwright, Oliver J. Müller, Honglin Xu, Sam Butterworth, Xin Wang   +16 more
wiley   +1 more source

Descriptive analysis of colour Doppler echocardiography results in neonates with congenital heart disease in eastern China: a retrospective cohort study. [PDF]

Front Pediatr
Wang H, Guo Q, Yu X.
europepmc   +1 more source

Automatic Assessment of Mitral Regurgitation Severity Using the Mask R-CNN Algorithm with Color Doppler Echocardiography Images. [PDF]

Comput Math Methods Med, 2021
Zhang Q, Liu Y, Mi J, Wang X, Liu X, Zhao F, Xie C, Cui P, Zhang Q, Zhu X.   +9 more
europepmc   +1 more source

Use of Pulsed-Wave Doppler Echocardiography to Measure Changes in MPAP: To the Editor [PDF]

, 1997
Brian J. Lipworth, David G. Kiely
openalex   +1 more source

Astragaloside IV alleviates hypoxic pulmonary hypertension by inhibiting RELM‐β to reduce PINK1/Parkin‐mediated mitophagy in pulmonary artery smooth muscle cells (PASMCs)

British Journal of Pharmacology, EarlyView.
Background and Purpose Hypoxic pulmonary hypertension (HPH) is a chronic disorder marked by irreversible pulmonary vascular remodelling (PVR) and pulmonary artery smooth muscle cell (PASMC) dysfunction. Astragaloside IV (AS‐IV), a natural saponin from Astragalus, shows potential in HPH management. This study explores AS‐IV's protective effect on PVR in
Rongzhen Ding, Haiping Xie, Shuliu Sang, Li Qin, Yinhui Sun, Chao Zhang, Jian Yi, Hui Liu, Jianmin Fan, Guoran Peng, BeiBei Cheng, Lan Song, Aiguo Dai   +12 more
wiley   +1 more source

Development of a Z-score equation for atrioventricular interval measurement by two-dimensional pulsed Doppler echocardiography in normal fetuses between 16 and 33+6 weeks of gestation. [PDF]

Ultrasonography
Amorim LADR, Bravo-Valenzuela NJ, Almeida SLM, Peixoto AB, Nicoloso LHS, Schmidt MM, Zielinsky P, Araujo Júnior E.   +7 more
europepmc   +1 more source

Two wrongs sometimes do make a right: errors in aortic valve stenosis assessment by same-day Doppler echocardiography and 4D flow MRI. [PDF]

Int J Cardiovasc Imaging, 2022
Huh H, Lee J, Kinno M, Markl M, Thomas JD, Barker AJ.   +5 more
europepmc   +1 more source

The effects of halothane and isoflurane on cardiovascular function in laterally recumbent horses [PDF]

, 2005
A.L. Raisis, Akaike, Bennett, Berne, Borow, Branson, Brunson, DiCorte, Diggle, Dunlop, Dyson, Johnston, K Rogers, K.J. Blissitt, L.E. Young, Little, Lunn, Madan, Peters, Raisis, Raisis, Searle, Seymour, Singer, Singer, Singer, Steffey, Steffey, Steffey, Steffey, Steffey, Taylor, V Adams, Veenman, W Henley, Wagner, Wallmeyer, Young, Young   +38 more
core   +1 more source

Neural Organoids Protect Engineered Heart Tissues From Glucolipotoxicity by Transferring Versican in a Co‐Culture System

Cell Proliferation, EarlyView.
In this study, Bai et al. established a co‐culture system between neural organoids (NOs) and engineered heart tissues (EHTs) and demonstrated that NOs could secrete versican, which was absorbed by EHTs to ameliorate glucolipotoxicity. ABSTRACT Metabolic disorders could cause dysregulated glucose and lipid at the systemic level, but how inter‐tissue ...
Baochen Bai, Jiting Li, Ze Wang, Yuhan Yang, Jieqing He, Gonglie Chen, Yufan Zhang, Yan Qi, Zhongjun Wan, Lin Cai, Run Wang, Kai Wang, Dongyu Zhao, Jingzhong Zhang, Weihua Huang, Ronald X. Xu, Mingzhai Sun, Xiao Han, Yan Liu, Donghui Zhang, Wanying Zhu, Jian Liu, Yuxuan Guo   +22 more
wiley   +1 more source