Results 211 to 220 of about 14,072,652 (376)

Recoil-induced ultrafast molecular rotation probed by dynamical rotational Doppler effect. [PDF]

open access: yesProc Natl Acad Sci U S A, 2019
Céolin D   +11 more
europepmc   +1 more source

Trametinib alters contractility of paediatric Noonan syndrome‐associated hypertrophic myocardial tissue slices

open access: yesESC Heart Failure, EarlyView.
Abstract Aims No curative treatment is available for RASopathy‐associated childhood‐onset hypertrophic cardiomyopathy (RAS‐CM). Preclinical data and individual reports suggest a beneficial effect of small molecules targeting the RAS–mitogen‐activated protein (MAP) kinase (MAPK) pathway in severely affected RAS‐CM patients.
Jules Hamers   +11 more
wiley   +1 more source

The effect of trimetazidine on cardiac haemodynamics and mitochondrial function in wild‐type transthyretin amyloidosis

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Wild‐type transthyretin cardiac amyloidosis (ATTRwt) is a cardiomyopathy causing myocardial hypoperfusion and impaired cardiac mitochondrial function. Trimetazidine is an antianginal agent used in patients with stable angina pectoris, which improves cardiac contractility and mitochondrial function.
Bertil Thyrsted Ladefoged   +5 more
wiley   +1 more source

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