Results 111 to 120 of about 252,409 (330)

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

A Low-Cost and High-Precision Underwater Integrated Navigation System

Journal of Marine Science and Engineering
The traditional underwater integrated navigation system is based on an optical fiber gyroscope and Doppler Velocity Log, which is high-precision but also expensive, heavy, bulky and difficult to adapt to the development requirements of AUV swarm ...
Jiapeng Liu, Te Yu, Chao Wu, Chang Zhou, Dihua Lu, Qingshan Zeng   +5 more
doaj   +1 more source

1645 nm coherent Doppler wind lidar with a single-frequency Er:YAG laser.

Optics Express, 2020
Solid-state single-frequency lasers around 1.6 µm are ideal sources for coherent Doppler wind lidars (CDWLs). A CDWL system with 1645 nm sing-frequency, injection-seeded Er:YAG ceramic laser is demonstrated.
Kaixin Wang, Chunqing Gao, Zhifeng Lin, Qing Wang, M. Gao, Shuai Huang, Chaoyong Chen   +6 more
semanticscholar   +1 more source

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

2-D Coherent Integration Processing and Detecting of Aircrafts Using GNSS-Based Passive Radar

Remote Sensing, 2018
Long time coherent integration is a vital method for improving the detection ability of global navigation satellite system (GNSS)-based passive radar, because the GNSS signal is not radar-designed and its power level is very low.
Hong-Cheng Zeng, Jie Chen, Peng-Bo Wang, Wei Yang, Wei Liu   +4 more
doaj   +1 more source

Open questions on prominences from coordinated observations by IRIS, Hinode, SDO/AIA, THEMIS, and the Meudon/MSDP

, 2014
Context. A large prominence was observed on September 24, 2013, for three hours (12:12 UT -15:12 UT) with the newly launched (June 2013) Interface Region Imaging Spectrograph (IRIS), THEMIS (Tenerife), the Hinode Solar Optical Telescope (SOT), the Solar ...
A. López Ariste, B. Schmieder, H. Tian, K. Dalmasse, L. Golub, N. Mein, P. Mein, T. Kucera   +7 more
core   +2 more sources

Measuring cerebral hemodynamic changes during action observation with functional transcranial doppler

Journal of Physical Therapy Science, 2015
[Purpose] The purpose of this study was to investigate the effects of action observation training (AOT) on cerebral hemodynamic changes including cerebral blood flow velocity (CBFV) and cerebral blood flow volume (CBFvol) in healthy subjects.
Seong-Sik Kim, Byoung-Hee Lee
semanticscholar   +1 more source

Data‐Driven Feedback Identifies Focused Ultrasound Exposure Regimens for Improved Nanotheranostic Targeting of the Brain

Advanced Science, EarlyView.
Machine learning models predict in real time the onset of harmful microbubble collapse during microbubble‐enhanced focused ultrasound (MB‐FUS) and enable dynamic adjustment of sonication to prevent cavitation‐induced damage. This predictive control expands the safe operating window for bloodbrain barrier opening, enhancing nanoparticle delivery and ...
Hohyun Lee, Victor Menezes, Shiqin Zeng, Chulyong Kim, Cynthia M. Baseman, Jae Hyun Kim, Samhita Padmanabhan, Pranav Premdas, Naima Djeddar, Anton Bryksin, Nikhil Pandey, Pavlos Anastasiadis, Anthony J. Kim, Tobey J. MacDonald, Chetan Bettegowda, Graeme F. Woodworth, Felix J. Herrmann, Costas Arvanitis   +17 more
wiley   +1 more source

Real‐Time and High‐Resolution NIR‐II‐L Imaging of Netrin‐1‐Mediated Neurovascular Coupling Driven by Dose‐Dependent Electroacupuncture

Advanced Science, EarlyView.
Disrupted neurovascular coupling contributes to ovarian dysfunction in polycystic ovary syndrome. Using near‑infrared II long‑wavelength imaging, this study visualizes how electroacupuncture dynamically regulates ovarian blood vessels in vivo. Immediate and cumulative stimulation elicit distinct vascular responses via a Netrin‐1 dependent mechanism ...
Yicong Wang, Zi‐Han Chen, Jiajia Li, Wei Hu, Ying Cao, Yu Wang, Xiaoyu Tong, Wenhan Lu, Yuze Yang, Yuehao Wang, Yan Xiao, Wenhao Gao, Yuning Chen, Yuyan Hou, Fan Zhang, Yi Feng   +15 more
wiley   +1 more source

Soft, Flexible, and Stretchable Platforms for Tissue‐Interfaced Bioelectronics

Advanced Science, EarlyView.
Bio‐integrated electronics provide mechanically compliant and stable interfaces with soft biological tissues. Representative applications include neural interfaces, wet‐organadhesive electronics, and skin‐interfaced devices. E represents Young´s modulus and ε represents strain.
Kento Yamagishi, Sunghoon Lee, Tomoyuki Yokota, Takao Someya   +3 more
wiley   +1 more source