Results 141 to 150 of about 5,549 (198)

Delayed resistance selection for doripenem when passaging Pseudomonas aeruginosa isolates with doripenem plus an aminoglycoside

Diagnostic Microbiology and Infectious Disease, 2006
Doripenem (formerly S-4661), a parenteral carbapenem, was tested in combination with an aminoglycoside (gentamicin) to determine the resistance selection of these codrugs during subinhibitory passaging using 6 Pseudomonas aeruginosa isolates. The organisms were selected based on doripenem and gentamicin MIC values to include isolates with MIC values ...
Holly Huynh, Ronald N Jones
exaly   +3 more sources

Doripenem: position in clinical practice

Expert Review of Anti-Infective Therapy, 2009
Doripenem is a novel carbapenem with a broad spectrum of activity against Gram-positive pathogens, anerobes and Gram-negative bacteria, including Pseudomonas aeruginosa. Doripenem exhibits rapid bactericidal activity with two- to fourfold lower MIC values for Gram-negative bacteria, compared with other carbapenems such as imipenem.
Harakh V, Dedhia, Richard, McKnight
exaly   +3 more sources

Antimicrobial activity of doripenem (S-4661): a global surveillance report (2003) [PDF]

open access: yesClinical Microbiology and Infection, 2005
The spectrum of activity and potency of doripenem, a broad-spectrum parenteral carbapenem currently in clinical development, was evaluated using 16 008 clinical bacterial isolates collected as part of an international surveillance project during 2003 ...
Ronald N Jones, R N Jones, T R Fritsche
exaly   +2 more sources

Doripenem: antimicrobial profile and clinical potential

Diagnostic Microbiology and Infectious Disease, 2009
David Livermore
exaly   +4 more sources

Antimicrobial activities of doripenem and other carbapenems against Pseudomonas aeruginosa, other nonfermentative bacilli, and Aeromonas spp.

open access: yesDiagnostic Microbiology and Infectious Disease, 2009
The in vitro activity of doripenem against prevalent nonfermentative Gram-negative bacilli and Aeromonas spp. was evaluated. The collection comprised 14979 nonduplicate clinical isolates submitted during a global Doripenem Surveillance Program conducted ...
David Livermore   +2 more
exaly   +2 more sources

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