Results 331 to 340 of about 229,236 (394)

Phase‐Change Materials for Volatile Threshold Resistive Switching and Neuronal Device Applications

Advanced Science, EarlyView.
Volatile threshold switching materials are an important pathway to simulate neuronal behavior. This review summarizes recent advances in the development of volatile resistive switching devices and neuronal oscillators based on three representative phase change materials, emphasizes the major challenges in this rapidly evolving field, and provides an ...
Huandong Chen, Jayakanth Ravichandran
wiley   +1 more source

Comparative transcriptome analysis reveal gene regulation of dormancy release in <i>Cardiocrinum giganteum</i> seeds induced by temperature. [PDF]

Front Plant Sci
Li Y, Li X, Li F, Wang L, Li H, Zhao Y, Guan W.   +6 more
europepmc   +1 more source

Discovery of a Potent and Selective TEAD Degrader with Durable Degradation Activity

Advanced Science, EarlyView.
KG‐FP‐003, a highly potent TEAD‐YAP PROTAC derived from the patented inhibitor is developed. It selectively degrades endogenous TEAD proteins in HiBiT systems without IMiD‐related off‐target effects. Screening across 867 cancer cell lines revealed broad and superior anti‐tumor activity, highlighting its therapeutic potential through targeted TEAD ...
Linhui Cao, Jing Yang, Yuhang Liu, Xiaotong Chen, Yufang Shi, Yunshuo Zhao, Yong Zhang, Jian Chen, Bowen Li, Wuqiang Wen, Lu Chen, Bo Peng, Lu Huang, Yanli Sun, Lixin Zhou, Matthew G Rees, Melissa M Ronan, Jennifer A Roth, Zhixiang Guo, Jing Xing, Guangya Zhu, Yazhou Wang, Baishan Jiang, Jing Lu, Kehao Zhao, Wenchao Lu   +25 more
wiley   +1 more source

A Replicable and Generalizable Neuroimaging‐Based Indicator of Pain Sensitivity Across Individuals

Advanced Science, EarlyView.
Humans differ in their sensitivity to pain. With six large and diverse fMRI datasets (total N = 1046), this study finds that such individual differences in pain sensitivity can be tracked by fMRI responses to painful stimuli. A highly generalizable machine learning model is further built to predict pain sensitivity across all datasets and analgesic ...
Li‐Bo Zhang, Xue‐Jing Lu, Hui‐Juan Zhang, Zhao‐Xing Wei, Ya‐Zhuo Kong, Yi‐Heng Tu, Gian Domenico Iannetti, Li Hu   +7 more
wiley   +1 more source

The Duality of Collagens in Metastases of Solid Tumors. [PDF]

Int J Mol Sci
Carnazza M, Quaranto D, DeSouza N, Li XM, Tiwari RK, Di Martino JS, Geliebter J.   +6 more
europepmc   +1 more source

Gene Regulatory Changes Associated With Phenological Transitions in an Ecologically Significant Tree Species. [PDF]

Plant Environ Interact
Caso-McHugh T, Des Marais DL, Oseguera M, Blumstein M.   +3 more
europepmc   +1 more source

Editorial: Dormant Cancer Cells, Cancer Progression, and Post-Acute Sequelae of COVID-19 and Influenza. [PDF]

Med Sci Monit
Parums DV.
europepmc   +1 more source

Global Patterns in the Evolutionary Relations Between Seed Mass and Germination Traits. [PDF]

Ecol Evol
Maleki K, Vandelook F, Saatkamp A, Maleki K, Heshmati S, Soltani E.   +5 more
europepmc   +1 more source