Results 191 to 200 of about 3,028,573 (310)

NR2F1 and mTORC1 provide the bridge between melanoma dormancy and therapeutic resistance. [PDF]

J Clin Invest
Mamidi N, Das SK, Fisher PB.
europepmc   +1 more source

Interacting effects of genetic variation for seed dormancy and flowering time on phenology, life history, and fitness of experimental Arabidopsis thaliana populations over multiple generations in the field.

New Phytologist, 2017
M. Taylor, M. Cooper, Reena Sellamuthu, Peter Braun, Andrew Migneault, Alyssa Browning, Emily Perry, J. Schmitt   +7 more
semanticscholar   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source

Paving the way to secondary dormancy: mind the DOG's tail. [PDF]

Plant Physiol
Cao D.
europepmc   +1 more source

Transcriptome and Degradome Sequencing Reveals Dormancy Mechanisms of Cunninghamia lanceolata Seeds1

Plant Physiology, 2016
Dechang Cao, Huimin Xu, Yuanyuan Zhao, X. Deng, Yong-xiu Liu, W. Soppe, Jinxing Lin   +6 more
semanticscholar   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Decapitation Rapidly Triggers Axillary Bud Release via Regulatory Network Reprogramming in <i>Nicotiana tabacum</i>. [PDF]

Plants (Basel)
Xu B, Liu Q, Wang G, Shao S, Zhao P, Xia Q.   +5 more
europepmc   +1 more source

NIR‐Triggered Upconversion‐Perovskite Heterostructures for Non‐Genetic, Implant‐Free Optoelectronic Neuromodulation

Advanced Science, EarlyView.
The Single‐Nanostructured Optoelectronic Vehicle for neuromodulation Activation (SNOVA) establishes a paradigm for non‐genetic, implant‐free neuromodulation. By integrating NIR‐excitable UCNPs with broadband‐absorbing perovskite QDs, SNOVA efficiently converts deeply penetrating light into localized electric fields that modulate neuronal ion dynamics ...
Luyue Jiang, Chenguang Ma, Yiping Zhao, Jiazhi Li, Gen Li, Shuang Jin, Haoyang Su, Ye Tian, Yingkang Yang, Yunfu Luo, Lei Huang, Peijie Chen, Yiming Gao, Yi Wei, Yike Xiang, Lunming Qin, Kaihuan Zhang, Yifei Ye, Pengyi Tang, Liuyang Sun   +19 more
wiley   +1 more source

Remodeling the tumor dormancy ecosystem to prevent recurrence and metastasis. [PDF]

Signal Transduct Target Ther
Liang Y, Chen WM, Zhang Y, Li L.
europepmc   +1 more source

ABA and chromatin remodelling regulate the activity-dormancy cycle in hybrid aspen

, 2011
One of the most important survival strategies plants have evolved is the cessation of growth and development of dormancy in response to the seasonal changes. Apical meristems of deciduous woody plants living in temperate and boreal zones undergo a yearly cycle between an active and a dormant state, which allows them to protect the meristem and avoid ...
openaire   +1 more source