Results 221 to 230 of about 18,218 (324)

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

Advanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen, Fugui Zhang, Yifei Xiao, Xuejun Jiang, Zhiqian Yan, Jinyi Wang, Xiting Lv, Jialu Cui, Linna Ha, Hui Chen, Yongkang Dang, Zifei Qin, Jing Yang, Baojian Wu   +13 more
wiley   +1 more source

Broad active metabolic pathways, autophagy, and antagonistic hormones regulate dinoflagellate cyst dormancy in marine sediments. [PDF]

Sci Adv
Deng Y, Yue C, Yang H, Li F, Hu Z, Shang L, Chai Z, Lin S, Tang YZ.   +8 more
europepmc   +1 more source

Cell cycle arrest in plants: what distinguishes quiescence, dormancy and differentiated G1?

, 2017
Yazhini Velappan, Santiago Signorelli, Michael Considine   +2 more
openalex   +1 more source

ER‐phagy Activation by AMFR Attenuates Cardiac Fibrosis Post‐Myocardial Infarction via mTORC1 Pathway

Advanced Science, EarlyView.
By catalyzing FAM134B ubiquitination and activating ER‐phagy, AMFR alleviates progressive fibrosis and cardiac dysfunction by inhibiting the mTORC1 pathway. Consequently, these findings underscore the essential role of AMFR‐driven ER‐phagy in mitigating the progression of fibrotic responses, offering a potential therapeutic target for preventing heart ...
Zhixiang Wang, Kaifan Niu, Wei Liu, Xinyun Wang, Boshen Yang, Taixi Li, Yizhi Chen, Yuanyuan Jin, Yu Chen, Yangyi Lin, Xian Jin   +10 more
wiley   +1 more source

Whole-genome meta-analysis coupled with haplotype analysis reveal new genes and functional haplotypes conferring pre-harvest sprouting in rice. [PDF]

BMC Plant Biol
Aloryi KD, Okpala NE, Amenyogbe MK, Bimpong D, Karikari B, Guo H, Bello SF, Akaba S, Yeboah A, Ahmed AR, Ngegba PM, Kamara N, Anyanwu JN, Essandoh DA, Qiu X, Tian X, Wang G, An T.   +17 more
europepmc   +1 more source

Cancer reversion with oocyte extracts is mediated by cell cycle arrest and induction of tumour dormancy

, 2018
Norazalina Saad, Ramiro Alberio, Andrew D. Johnson, Richard D. Emes, Tom Giles, Philip A. Clarke, Anna M. Grabowska, Cinzia Allegrucci   +7 more
openalex   +2 more sources

A ROS‐Responsive Dual‐Targeting Drug Nanocarrier Serving as a GSI Synergist and Ferroptosis Sensitizer for T‐Cell Acute Lymphoblastic Leukemia

Advanced Science, EarlyView.
A self‐assembling nanotherapeutic strategy is designed—CD38‐PHD/G‐NPs, which released γ‐secretase inhibitor first, followed by adaptive dihydroartemisnin release in response to elevated reactive oxygen species levels. This controlled, sequential release strategy maximizes the synergistic anti‐leukemic efficacy of two agents with distinct mechanisms of ...
Ruinan Jia, Yang Liu, Jilong Xiao, Yuan Xia, Xin Zhao, Huixian Ma, Jingjing Ye, Zhiyue Zhang, Tao Sun, Chunyan Ji   +9 more
wiley   +1 more source

Beyond floral initiation: the role of flower bud dormancy in flowering time control of annual plants. [PDF]

J Exp Bot
Penfield S.
europepmc   +1 more source

Tumor dormancy: potential therapeutic target in tumor recurrence and metastasis prevention [PDF]

, 2013

core   +1 more source

A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness

Advanced Science, EarlyView.
This study identifies a sub‐circuit within the circadian pacemaker suprachiasmatic nucleus (SCN) that promotes arousal. This sub‐circuit is labeled by the clock output molecule mWAKE, which suppresses its excitability in a time‐dependent manner. mWAKE‐expressing cells in the SCN (SCNmWAKE cells) project to the subparaventricular zone (SPZ) to mediate ...
Qiang Liu, Sang Soo Lee, Jiali Xiong, Shahin Ahmadi, Benjamin J. Bell, Mehmet F. Keles, Mark N. Wu   +6 more
wiley   +1 more source