Results 241 to 250 of about 3,028,573 (310)

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Modeling a mesenchymal cell state by bioprinting for the molecular analysis of dormancy in melanoma. [PDF]

Mater Today Bio
Schmidt SK, Fischer S, El Ahmad Z, Schmid R, Metzger E, Schüle R, Hellerbrand C, Arkudas A, Kengelbach-Weigand A, Kappelmann-Fenzl M, Bosserhoff AK.   +10 more
europepmc   +1 more source

Biomimetic Multiscale‐Structured Biomass Graphene/Polyurethane Sponge Composite for Flexible Pressure Sensors and Intelligent Cushioning Materials

Advanced Science, EarlyView.
In this study, a multifunctional conductive sponge composite (MAPU) is developed using a biomimetic, hierarchical construction strategy emulating the growth process of natural wood. This approach involved integrating biomass‐derived graphitic nanoflakes, synthesized from luffa vine (LVGN), into a polyurethane (PU) sponge matrix.
Runmin Xu, Pusen Cao, Tingting Zhang, Jie Wei, Yue Wang, Zhi Huang, Zhenghang Chen, Jianfeng Xi, Yong Guo, Yuxia Chen   +9 more
wiley   +1 more source

Towards understanding cancer dormancy over strategic hitching up mechanisms to technologies. [PDF]

Mol Cancer
Yang S, Seo J, Choi J, Kim SH, Kuk Y, Park KC, Kang M, Byun S, Joo JY.   +8 more
europepmc   +1 more source

Dynamic gene regulatory networks drive seed dormancy and germination of Pinus tabuliformis. [PDF]

BMC Plant Biol
Li Y, Lu D, Zuo X, Zhang Y, Bu Y, Niu S, Lin J, Cui Y.   +7 more
europepmc   +1 more source

Seed dormancy cycling: A driver of germination timing in a facultative winter annual

Jianchang Yang, Yan Luo, Jerry M. Baskin, Carol C. Baskin, Andréas Prinzing, Luping Liu, Chaohan Xu, Keliang Zhang   +7 more
openalex   +1 more source

Seasons and shape: inflorescences from autumn to summer. [PDF]

J Exp Bot
González-Suárez P, Lock T, Penfield S, Hepworth J.   +3 more
europepmc   +1 more source

Overexpression of Tempranillo-Like Proteins Promotes Dormancy Release in Poplar. [PDF]

Plant Cell Environ
Gómez-Soto D, Triozzi PM, Conde D, Del Barrio C, Allona I, Perales M.   +5 more
europepmc   +1 more source

Targeted Therapies in the Most Common Advanced Solid Tumors, Drug Resistance, and Counteracting Progressive Micrometastatic Disease: The Next Frontier of Research. [PDF]

MedComm (2020)
Nicolini A, Ferrari P, Silvestri R, Bini DA.   +3 more
europepmc   +1 more source

HES1 oscillations are required for cell cycle re-entry in oestrogen receptor positive breast cancer cells

Cottrell O, Rowntree A, Chopra K, Mackellar E, Noble B, Dixon H, Healy C, Clarke RB, Papalopulu N.   +8 more
europepmc   +1 more source