Results 41 to 50 of about 75,269 (250)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Perceived width of the dorsum and palm.

open access: yes, 2020
Mean differences from accurate when dorsum of the hand (left panel) or palm (right panel) was distorted in the width dimension for each viewing orientation. Positive and negative scores represent overestimation and underestimation respectively.
Laurence R. Harris (8611452)   +1 more
core   +1 more source

The role of internal sutures in stabilization of nasal dorsum in primary rhinoplasty

open access: yes, 2021
© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.Background: Nasal dorsum anatomy is disrupted in rhinoplasty operations.
DEMİR, CAN İLKER   +3 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Evaluation of various options for resurfacing of soft-tissue defects of dorsum of hand and their outcome assessment

open access: yesAsian Journal of Medical Sciences, 2022
Background: Soft tissue defect of dorsum of hand is a difficult problem to deal with in reconstructive surgery. Various factors have to be considered for planning of the reconstruction.
Sasanka Nath   +3 more
doaj   +1 more source

Use of data to inform expert evaluative opinion in the comparison of hand images:the importance of scars [PDF]

open access: yes, 2013
Evaluation of a likelihood ratio is widely recognised as the most logical and appropriate means of assessing and expressing the weight of expert scientific evidence.
Jackson, Graham   +3 more
core   +1 more source

A new preservation technique for dehumping the dorsum

open access: yes, 2023
OBJECTIVE: We aimed to offer a new preservation strategy for dehumping the dorsum by using a variation of the cartilage push- down ( Ishida ...
Dundar, R.   +3 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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