Results 101 to 110 of about 653,512 (354)
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
THE ACTION OF ALLELIC FORMS OF THE GENE A IN MAIZE. I. STUDIES OF VARIABILITY, DOSAGE AND DOMINANCE RELATIONS. THE DIVERGENT CHARACTER OF THE SERIES [PDF]
, 1948 John R. Laughnan
openalex +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
In vitro-in vivo evaluation of a sustained release phenylpropanolamine oral dosage form [PDF]
, 1982 There is increasing interest in measuring pharmacokinetic parameters of phenylpropanolamine (PPA), a sympathomimetic amine used in over-the-counter nasal decongestants and anorectic formulations.
Dowse, R, Haigh, J M, Kanfer, I
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Role and Safety of Excipients in Syrups (Review)
Регуляторные исследования и экспертиза лекарственных средствINTRODUCTION. Syrups are an important dosage form used in medical practice, particularly in paediatrics. As of January 2024, there are 212 medicinal products formulated as syrups approved in the Russian Federation.
V. V. Kosenko +4 more
doaj +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
EFEKTIVITAS DOSIS KAPORIT DALAM MENURUNKAN KADAR AMONIAK LIMBAH CAIR RSUP Dr. SARDJITO YOGYAKARTA [PDF]
, 2007 Amoniak adalah senyawa yang terbentuk dari oksidasi bahan organik yang mengandung bahan nitrogen dalam air limbah dengan bantuan bakteri. Adanya amoniak dalam effluent air limbah dapat menjadi indikasi adanya pencemaran senyawa organik yang mengandung ...
RIYANTI, SRI
core
SUPPOSITORIES: ASPECTS OF DOSAGE FORM MODERNIZATION
Разработка и регистрация лекарственных средств, 2019 In this material were reviewed biopharmaceutical aspects of suppositories – described the relation between rectal route of administration, bioaccessibility and principles of dosage forms formulation.
N. B. Diomina, M. N. Anurova
doaj
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source