Results 151 to 160 of about 11,975,902 (386)

Improved Rp- Hplc Method for the Simultaneous Estimation of Tranexamic Acid and Mefenamic Acid in Tablet Dosage Form

, 2011
Subramanian Natesan, Devipriyadharshini Thanasekaran, Venkateshwaran Krishnaswami, Chandrasekar Ponnusamy   +3 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Named Entity Recognition in Electronic Health Records Using Transfer Learning Bootstrapped Neural Networks

, 2019
Neural networks (NNs) have become the state of the art in many machine learning applications, especially in image and sound processing [1]. The same, although to a lesser extent [2,3], could be said in natural language processing (NLP) tasks, such as ...
Gligic, Luka, Goldberg, Paul, Kormilitzin, Andrey, Nevado-Holgado, Alejo   +3 more
core  

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Neuroprotective effect and preparation methods of berberine

Frontiers in Pharmacology
Berberine (BBR) is a natural alkaloid, which has played an important role in the field of medicine since its discovery in the late 19th century. However, the low availability of BBR in vivo prevents its full effect.
Yi-Xuan Sunhe, Yue-Hui Zhang, Rui-Jia Fu, Ding-Qiao Xu, Yu-Ping Tang   +4 more
doaj   +1 more source

UHPLC Specific Method for Simultaneous Determination of Probable Impurities of Ezetimibeand Simvastatin in Combined Dosage Form [PDF]

Anantha Lakshmi Vadivelu, S. P. Vittal, Duvvuri Suryakala   +2 more
openalex   +1 more source

Globule Dosage Form

Definitions, 2020

semanticscholar   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Method Development and Its Validation for Simultaneous Estimation of Domperidone and Esomeprazole by RP-HPLC in Combination Tablet Dosage Form

, 2016
V. Tejasvi Reddy, Suresh Kumar, M. Akiful Haque, Vasudha Bakshi   +3 more
openalex   +1 more source

Topical Dosage Form

Definitions, 2020

semanticscholar   +1 more source