Results 31 to 40 of about 11,975,902 (386)

Adverse immunological responses against non-viral nanoparticle (NP) delivery systems in the lung

Journal of Immunotoxicology, 2021
There is a large, unmet medical need to treat chronic obstructive pulmonary disease, asthma, idiopathic pulmonary fibrosis and other respiratory diseases.
Leonor de Braganca, G. John Ferguson, Jose Luis Santos, Jeremy P. Derrick   +3 more
doaj   +1 more source

Stability of Extemporaneously Prepared Rufinamide Oral Suspensions [PDF]

, 2010
Background: Rufinamide is an oral antiepileptic drug indicated for adjunctive therapy in treating generalized seizures associated with Lennox-Gastaut syndrome. Currently, rufinanide is available as 200-mg and 400-mg tablets. A liquid dosage form does not
Best, Robert, Hutchinson, David, Liou, Yayin, Zhao, Fang   +3 more
core   +2 more sources

Drug Prescriptions Requiring Compounding at a Canadian University Affiliated Pediatric Hospital: A Cross-Sectional Study

Children, 2023
Despite ongoing international efforts, many drugs administered to children must be compounded from dosage forms designed for adults because they remain unavailable in commercial formulations that suit their needs.
Émilie Kate Landry, Julie Autmizguine, Sophie Bérubé, Raphael Kraus, Marie-Élaine Métras, Denis Lebel, Catherine Litalien   +6 more
doaj   +1 more source

Patient acceptability, safety and access : A balancing act for selecting age-appropriate oral dosage forms for paediatric and geriatric populations [PDF]

, 2018
© 2017 Elsevier B.V. All rights reserved.The selection and design of age-appropriate formulations intended for use in paediatric and geriatric patients are dependent on multiple factors affecting patient acceptability, safety and access.
Ernest, Terry B., Liu, Fang, Ranmal, Sejal R., Walsh, Jennifer   +3 more
core   +2 more sources

Changing the pill: developments toward the promise of an ultra-long-acting gastroretentive dosage form

Expert Opinion on Drug Delivery, 2018
Introduction: The development of oral sustained release dosage forms has been a longstanding goal due to the potential for ease of administration, improved pharmacokinetics, reduced dosing frequency, and improved adherence.
David H. Altreuter, Ameya R. Kirtane, Tyler M. Grant, Cecilia Kruger, G. Traverso, Andrew M Bellinger   +5 more
semanticscholar   +1 more source

An epidemiological assessment of lens opacifications that impaired vision in patients injected with radium-224 [PDF]

, 1988
The incidence of lens opacifications that impaired vision (cataract) was analyzed among 831 patients who were injected with known dosages of 224Ra in Germany shortly after World War II.
Chmelevsky, D., Kellerer, Albrecht M., Mays, C. W., Spiess, H., Stefani, F.-H.   +4 more
core   +1 more source

Application of Fourier transform infrared (FTIR) spectroscopy coupled with multivariate calibration for quantitative analysis of curcuminoid in tablet dosage form

Journal of Applied Pharmaceutical Sciences, 2018
© 2018 Chairany Siregar et al. This is an open access article distributed under the terms of the Creative Commons Attribution License -NonCommercial-ShareAlikeUnported License (http://creativecommons.org/licenses/by-nc-sa/3.0/).
C. Siregar, S. Martono, A. Rohman
semanticscholar   +1 more source

Andrographis paniculata Dosage Forms and Advances in Nanoparticulate Delivery Systems: An Overview

Molecules, 2022
Andrographis paniculata is a well-known Asian medicinal plant with a major phytoconstituent of diterpene lactones, such as andrographolide, 14-deoxyandrographolide, and neoandrographolide. A World Health Organization (WHO) monograph on selected medicinal
Subashini Raman, Vikneswaran Murugaiyah, Thaigarajan Parumasivam   +2 more
doaj   +1 more source

Gene expression in Leishmania is regulated predominantly by gene dosage [PDF]

, 2017
Leishmania tropica, a unicellular eukaryotic parasite present in North and East Africa, the Middle East, and the Indian subcontinent, has been linked to large outbreaks of cutaneous leishmaniasis in displaced populations in Iraq, Jordan, and Syria. Here,
Berriman, Matthew, Beverley, Stephen M., Cotton, James A., Durrant, Caroline, Grigg, Michael E., Iantorno, Stefano A., Khan, Asis, Myler, Peter, Ouellette, Marc, Sacks, David L., Sanders, Mandy J., Warren, Wesley C., Weiss, Louis M.   +12 more
core   +3 more sources

Enhanced rational protein engineering to reduce viscosity in high-concentration IgG1 antibody solutions

mAbs
Subcutaneous (SC) delivery of therapeutic antibodies can offer multiple benefits to patients and healthcare providers, including convenience, time savings, and cost reduction.
Tyler J. Lefevre, Jenna G. Caldwell, Austin Gallegos, Qun Du, Erin Houston, Gilad Kaplan, Reza Esfandiary   +6 more
doaj   +1 more source