Results 31 to 40 of about 653,512 (354)

Tapentadol extended release for the management of chronic neck pain [PDF]

, 2017
BACKGROUND: The role of opioids in the management of chronic neck pain is still poorly investigated. No data are available on tapentadol extended release (ER).
Coluzzi, Flaminia
core   +1 more source

Optimisation study on the flavonoid extraction process from Abrus precatorius leaves and the comparison of total flavonoid content by HPLC and UV

Journal of Holistic Integrative Pharmacy, 2023
Abrus precatorius is a leguminous plant with high medicinal value. Its leaves are rich in flavonoids. There only are limited reports on the extraction process and quality assessment of total flavonoids in Abrus precatorius leaves (APL).
Xujiang Yuan, Cuimin He, Xianmei Xue, Zhike Liang, Yanfen Chen   +4 more
doaj  

Stability of Extemporaneously Prepared Rufinamide Oral Suspensions [PDF]

, 2010
Background: Rufinamide is an oral antiepileptic drug indicated for adjunctive therapy in treating generalized seizures associated with Lennox-Gastaut syndrome. Currently, rufinanide is available as 200-mg and 400-mg tablets. A liquid dosage form does not
Best, Robert, Hutchinson, David, Liou, Yayin, Zhao, Fang   +3 more
core   +2 more sources

Assessing subvisible particle risks in monoclonal antibodies: insights from quartz crystal microbalance with dissipation, machine learning, and in silico analysis

mAbs
Throughout the lifecycle of biopharmaceutical development and manufacturing, monoclonal antibodies (mAbs) are subjected to diverse interfacial stresses and encounter various container surfaces.
Yibo Wang, Alexis Hanford, Mehdi Boroumand, Cavan Kalonia, Jesse Leissa, Mitali Shah, Tony Pham, Theodore Randolph, Indira Prajapati   +8 more
doaj   +1 more source

Experimental determination of the velocity distribution in USP Apparatus 1 (basket apparatus) using Particle Image Velocimetry (PIV)

International Journal of Pharmaceutics: X, 2021
The USP Apparatus 1 (basket apparatus) is commonly used to evaluate the dissolution performance of oral solid dosage forms. The hydrodynamics generated by the basket contributes, in general, to the dissolution rate and hence the dissolution results. Here,
Chadakarn Sirasitthichoke, Satish Perivilli, Mark R. Liddell, Piero M. Armenante   +3 more
doaj  

Thermogravimetric studies of a nasal preparation with an interleukin-1β (IL-1Ra) antagonist

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021
Interleukin-1 receptor antagonist (IL-1Ra) is an active pharmaceutical ingredient obtained by the method of gene transformation of Escherichia coli, provides a neuroprotective effect, namely – inhibition of oxidative modification of proteins ...
B. S. Burlaka
doaj   +1 more source

Patient acceptability, safety and access : A balancing act for selecting age-appropriate oral dosage forms for paediatric and geriatric populations [PDF]

, 2018
© 2017 Elsevier B.V. All rights reserved.The selection and design of age-appropriate formulations intended for use in paediatric and geriatric patients are dependent on multiple factors affecting patient acceptability, safety and access.
Ernest, Terry B., Liu, Fang, Ranmal, Sejal R., Walsh, Jennifer   +3 more
core   +2 more sources

Multicomponent crystals: Solubility enhancement of simvastatin using arginine and glycine coformers [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Simvastatin can be modified by the formation of multicomponent crystals to increase its solubility. Aims: To compare the solubility of multicomponent simvastatin crystals to pure simvastatin. Methods: The in silico study of simvastatin and
Iyan Sopyan, Karyn Elizabeth, Sandra Megantara, Silmy Kaffah   +3 more
doaj   +1 more source

Electroanalytical determination of metronidazole in tablet dosage form [PDF]

Journal of the Serbian Chemical Society, 2013
In this study, the electrochemical reduction and determination of metronidazole were easily realized in Britton-Robinson buffer (pH = 4.01) using UTGE by cyclic voltammetric (CV) and differential pulse voltammetric (DPV) techniques.
Yilmaz Selehattin, Baltaoglu Esra, Saglikoglu Gulsen, Yagmur Sultan, Polat Kamran, Sadikoglu Murat   +5 more
doaj   +1 more source

Drug Repurposing and Dosage Form Development of Anti-COVID-19

Pharmaceutical Sciences and Research, 2021
The COVID-19 pandemic has been occurring approximately for more than 1 year. This pandemic has been a health issue that hits all countries in the world caused by the transmission of SARS-CoV-2 virus from one individual to another.
Kevin Kwok
doaj   +1 more source