Results 31 to 40 of about 916,770 (316)

Adverse immunological responses against non-viral nanoparticle (NP) delivery systems in the lung

open access: yesJournal of Immunotoxicology, 2021
There is a large, unmet medical need to treat chronic obstructive pulmonary disease, asthma, idiopathic pulmonary fibrosis and other respiratory diseases.
Leonor de Braganca   +3 more
doaj   +1 more source

Drug Prescriptions Requiring Compounding at a Canadian University Affiliated Pediatric Hospital: A Cross-Sectional Study

open access: yesChildren, 2023
Despite ongoing international efforts, many drugs administered to children must be compounded from dosage forms designed for adults because they remain unavailable in commercial formulations that suit their needs.
Émilie Kate Landry   +6 more
doaj   +1 more source

Predicting Dosage of Immunosuppressant Drugs After Kidney Transplantation Using Machine Learning [PDF]

open access: yesarXiv, 2023
While kidney transplants are seen as the best treatment option for patients with end-stage renal disease and kidney failure, the organ's health depends on the dosage of immunosuppressant drugs post-transplantation. Due to the dosage variance based on each patient's unique physiology, nephrologists face numerous difficulties when determining the precise
arxiv  

Selenium / Tellurium Two-Dimensional Structures: from Isovalent Se Dopants in Te to Atomically Thin Se Films [PDF]

open access: yesarXiv, 2023
Two-dimensional (2D) elemental semiconductors have great potential for device applications, but their performance is limited by the lack of efficient doping methods. Here, combining molecular beam epitaxy, scanning tunneling microscopy/spectroscopy, X-ray photoelectron spectroscopy, and density functional theory calculations, we investigate the ...
arxiv  

Mathematical modeling of tumor-immune system interactions: the effect of rituximab on breast cancer immune response [PDF]

open access: yes, 2021
tBregs are a newly discovered subcategory of B regulatory cells, which are generated by breast cancer, resulting in the increase of Tregs and therefore in the death of NK cells. In this study, we use a mathematical and computational approach to investigate the complex interactions between the aforementioned cells as well as CD8$^+$ T cells, CD4$^+$ T ...
arxiv   +1 more source

Polygalaxanthone III downregulates inflammation in the lipopolysaccharide-stimulated RAW264.7 macrophages: A quantibody array analysis

open access: yesJournal of Pharmacological Sciences, 2021
Polygala japonica Houtt. (PJ), a member of the Polygala L. family that is suggested to exhibit detoxification properties in traditional Chinese medicine, is often used to treat upper respiratory tract infections.
Yinan Wu   +7 more
doaj  

Optimisation study on the flavonoid extraction process from Abrus precatorius leaves and the comparison of total flavonoid content by HPLC and UV

open access: yesJournal of Holistic Integrative Pharmacy, 2023
Abrus precatorius is a leguminous plant with high medicinal value. Its leaves are rich in flavonoids. There only are limited reports on the extraction process and quality assessment of total flavonoids in Abrus precatorius leaves (APL).
Xujiang Yuan   +4 more
doaj  

Electroanalytical determination of metronidazole in tablet dosage form [PDF]

open access: yesJournal of the Serbian Chemical Society, 2013
In this study, the electrochemical reduction and determination of metronidazole were easily realized in Britton-Robinson buffer (pH = 4.01) using UTGE by cyclic voltammetric (CV) and differential pulse voltammetric (DPV) techniques.
Yilmaz Selehattin   +5 more
doaj   +1 more source

Assessing subvisible particle risks in monoclonal antibodies: insights from quartz crystal microbalance with dissipation, machine learning, and in silico analysis

open access: yesmAbs
Throughout the lifecycle of biopharmaceutical development and manufacturing, monoclonal antibodies (mAbs) are subjected to diverse interfacial stresses and encounter various container surfaces.
Yibo Wang   +8 more
doaj   +1 more source

Experimental determination of the velocity distribution in USP Apparatus 1 (basket apparatus) using Particle Image Velocimetry (PIV)

open access: yesInternational Journal of Pharmaceutics: X, 2021
The USP Apparatus 1 (basket apparatus) is commonly used to evaluate the dissolution performance of oral solid dosage forms. The hydrodynamics generated by the basket contributes, in general, to the dissolution rate and hence the dissolution results. Here,
Chadakarn Sirasitthichoke   +3 more
doaj  

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