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Dosage form design and development
Clinical Therapeutics, 2008Drugs must be properly formulated for administration to patients, regardless of age. Pediatric patients provide some additional challenges to the formulator in terms of compliance and therapeutic efficacy. Due to the lack of sufficient drug products for the pediatric population, the pharmaceutical industry and compounding pharmacies must develop and ...
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Expandable gastroretentive dosage forms
Journal of Controlled Release, 2003Expandable gastroretentive dosage forms (GRDFs) have been designed for the past 3 decades. They were originally created for possible veterinary use, but later the design was modified for enhanced drug therapy in humans. These GRDFs are easily swallowed and reach a significantly larger size in the stomach due to swelling or unfolding processes that ...
Eytan A, Klausner +3 more
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Evaluation of Dosage Forms. VI. Studies of Commercial Oxyphenbutazone Tablet Dosage Forms
Drug Development and Industrial Pharmacy, 1999Dissolution-dialysis studies of commercial tablets of oxyphenbutazone were carried out to establish the applicability of this technique for the in vitro evaluation of oxyphenbutazone dosage form. While disintegration time and dissolution rate studies did not give a true indication of bioavailability, an excellent correlation was obtained between the ...
B, Razdan, N V, Nagaraj
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Assessment of Dosage Forms In Vitro
1988This chapter presents descriptions of some in vitro tests which can be applied to pharmaceutical products, using some of the background physical chemistry discussed in other chapters. In particular, we will examine the influence of some of the key parameters of pharmaceutical systems, such as particle size, viscosity, adhesion or formulation in general
A. T. Florence, D. Attwood
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Evaluation of Dosage Forms. IV. Studies on Commercial Phenylbutazone Tablet Dosage Forms
Drug Development and Industrial Pharmacy, 1998In order to determine the feasibility of dissolution-dialysis as a suitable technique for in vitro evaluation, studies on commercial phenylbutazone tablets were carried out. Although disintegration time and dissolution parameters did not give a true indication of bioavailability, an excellent correlation was obtained between the dialysis rate constant (
B, Razdan, A R, Paradkar
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Dosage forms are the means by which drug molecules are delivered to sites of action within the body. They are essential for ensuring the safe, effective, and controlled delivery of medication to achieve the desired therapeutic effect. The introduction to dosage forms encompasses a wide range of formulations designed to meet various medical needs and ...
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