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2016
The dictionary definition of parenteral is nonenteral or nonoral and, therefore, strictly speaking, the term parenteral includes all products administered other than by the oral route. The pharmaceutical convention, however, is to use the term parenteral to describe medicines administered by means of an injection.
Mark Gibson, Joanne Broadhead
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The dictionary definition of parenteral is nonenteral or nonoral and, therefore, strictly speaking, the term parenteral includes all products administered other than by the oral route. The pharmaceutical convention, however, is to use the term parenteral to describe medicines administered by means of an injection.
Mark Gibson, Joanne Broadhead
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Dosage form design and development
Clinical Therapeutics, 2008Drugs must be properly formulated for administration to patients, regardless of age. Pediatric patients provide some additional challenges to the formulator in terms of compliance and therapeutic efficacy. Due to the lack of sufficient drug products for the pediatric population, the pharmaceutical industry and compounding pharmacies must develop and ...
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Expandable gastroretentive dosage forms
Journal of Controlled Release, 2003Expandable gastroretentive dosage forms (GRDFs) have been designed for the past 3 decades. They were originally created for possible veterinary use, but later the design was modified for enhanced drug therapy in humans. These GRDFs are easily swallowed and reach a significantly larger size in the stomach due to swelling or unfolding processes that ...
Eytan Klausner +3 more
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Evaluation of Dosage Forms. VI. Studies of Commercial Oxyphenbutazone Tablet Dosage Forms
Drug Development and Industrial Pharmacy, 1999Dissolution-dialysis studies of commercial tablets of oxyphenbutazone were carried out to establish the applicability of this technique for the in vitro evaluation of oxyphenbutazone dosage form. While disintegration time and dissolution rate studies did not give a true indication of bioavailability, an excellent correlation was obtained between the ...
Balkishen Razdan, N. V. Nagaraj
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Evaluation of Dosage Forms. IV. Studies on Commercial Phenylbutazone Tablet Dosage Forms
Drug Development and Industrial Pharmacy, 1998In order to determine the feasibility of dissolution-dialysis as a suitable technique for in vitro evaluation, studies on commercial phenylbutazone tablets were carried out. Although disintegration time and dissolution parameters did not give a true indication of bioavailability, an excellent correlation was obtained between the dialysis rate constant (
Balkishen Razdan, Anant Paradkar
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1979
Pharmaceutical aerosols are packaged under pressure and contain therapeutically active ingredients. They are intended for topical application to the skin as well as local application, including inhalation.
W. T. Lowry, James C. Garriott
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Pharmaceutical aerosols are packaged under pressure and contain therapeutically active ingredients. They are intended for topical application to the skin as well as local application, including inhalation.
W. T. Lowry, James C. Garriott
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Assessment of Dosage Forms In Vitro
1988This chapter presents descriptions of some in vitro tests which can be applied to pharmaceutical products, using some of the background physical chemistry discussed in other chapters. In particular, we will examine the influence of some of the key parameters of pharmaceutical systems, such as particle size, viscosity, adhesion or formulation in general
D. Attwood, A. T. Florence
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Disintegrants in Solid Dosage Forms
Drug Development and Industrial Pharmacy, 1990AbstractThe dynamic approach to tablet disintegration, which is based on the measurement of the force that develops inside the compact upon water entrance, is basically taken up.The combined measurements of force development and water uptake, simultaneously effected on the same compact, provide a novel parameter that is proposed to quantify and compare
CARAMELLA, CARLA MARCELLA +3 more
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1996
All drugs are administered to the body in some type of dosage form that consists of the active ingredient plus other inactive components, commonly known as excipients. The objective of the pharmaceutical formulator is to prepare a convenient-to-administer, aesthetically acceptable dosage form that presents an accurate and precise amount of a physically
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All drugs are administered to the body in some type of dosage form that consists of the active ingredient plus other inactive components, commonly known as excipients. The objective of the pharmaceutical formulator is to prepare a convenient-to-administer, aesthetically acceptable dosage form that presents an accurate and precise amount of a physically
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Annals of Internal Medicine, 1970
Excerpt To the editor: In their article entitled "An Improved Method of Digitoxin Therapy" (Ann Intern Med72: 453-464, 1970), Jelliffe and co-workers stated under Dosage Forms of Digitoxin (p.
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Excerpt To the editor: In their article entitled "An Improved Method of Digitoxin Therapy" (Ann Intern Med72: 453-464, 1970), Jelliffe and co-workers stated under Dosage Forms of Digitoxin (p.
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