Results 181 to 190 of about 707,752 (308)

Testing for Similarity of Dose Response in Multiregional Clinical Trials. [PDF]

Stat Med
Dette H, Koletzko L, Bretz F.
europepmc   +1 more source

Sleep Matters: Exploring the Link Between Sleep Disturbances and Fatigue in Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Fatigue is a prevalent and debilitating symptom for patients with rheumatoid arthritis (RA). Although patients and rheumatologists often attribute fatigue to inflammation, other factors such as sleep disturbances are frequently overlooked. This study aims to explore the relationship between subjective (self‐reported) and objective (actigraphy
Natalia V. Chalupczak, Burcu Aydemir, Ariel Isaacs, Lutfiyya N. Muhammad, Jing Song, Kathryn J. Reid, Daniela Grimaldi, Mary Carns, Kathleen Dennis‐Aren, Dorothy D. Dunlop, Beth I. Wallace, Phyllis C. Zee, Yvonne C. Lee   +12 more
wiley   +1 more source

Population Pharmacokinetics and Exposure-Response Analysis of Serplulimab in Small Cell Lung Cancer Patients. [PDF]

Clin Transl Sci
Wang K, Shen Y, Hu C, Xu F, Wang Q, Gao Y, Zhou L.   +6 more
europepmc   +1 more source

Where, how, and how much? A multicenter cohort study of the relationship between lupus decision aid modality, place of administration, interruption and viewing completeness and patient‐reported outcomes

Arthritis Care &Research, Accepted Article.
Objective We assessed whether shared decision‐making (SDM), and patient acceptability, feasibility, and overall satisfaction with a computerized patient decision aid (PtDA) for patients with systemic lupus erythematosus (SLE), differs by PtDA setting, modality, and the viewing experience.
Jasvinder A. Singh, Mark Beasley, Larry R. Hearld, for the Implementing DEcision‐Aid for Lupus in clinics (IDEAL) Consortium   +3 more
wiley   +1 more source

Environmental causes of human congenital malformations: The physician\u27s role in dealing with these complex clinical problems caused by environmental and genetic factors. [PDF]

, 2008
Brent, Robert L
core   +1 more source

Treating lupus nephritis patients to lupus low disease activity reduces renal relapse and preserves long‐term kidney function

Arthritis Care &Research, Accepted Article.
Objective Lupus low disease activity state (LLDAS) is a validated treatment target in systemic lupus erythematosus (SLE) but limited studies have explored the role of LLDAS in lupus nephritis (LN). This study aims to investigate the frequency and predictors of LLDAS attainment, and its benefit on LN relapse and renal function preservation in patients ...
Chak Kwan Cheung, Desmond YH Yap, KL Lee, Philip H Li, Iris YK Tang, Chak Sing Lau, Shirley CW Chan   +6 more
wiley   +1 more source

Potential Drug Dose-Specific Adverse Three-Drug Combinations: A US Insurance Claims Data-Based Study. [PDF]

Pharmacoepidemiol Drug Saf
Shi Y, Sun A, Chiang CW, Yang Y, Hunold KM, Xu J, Russo M, Caterino J, Eadon MT, Li L, Su J, Donneyong M, Zhang P.   +12 more
europepmc   +1 more source

Development of a personalized visualization and analysis tool to improve clinical care in complex multisystem diseases with application to scleroderma

Arthritis Care &Research, Accepted Article.
Background In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of a scleroderma patient's ...
Ji Soo Kim, John Scott, Lauren Fisher, Lauren N. Smith, Willie Stewart, Adrianne Woods, Rob Smithwright, Diane Koher, Parastoo Aslanbeik, Aalok B. Shah, Brad Tibbils, Samantha I. Pitts, Ayse P. Gurses, Yushi Yang, Ana‐Maria Orbai, Antony Rosen, Laura K. Hummers, Scott L. Zeger, Ami A. Shah   +18 more
wiley   +1 more source

The cardiac work-loop technique:An in vitro model for identifying and profiling drug-induced changes in inotropy using rat papillary muscles [PDF]

, 2020
AJ Taberner, AM Aylin, AW Tank, CW Scott, D Burkhoff, D Mehra, DA Eisner, DM Bers, DR Varma, E Takimoto, FG Spinale, H Lüllman, J Layland, J Layland, J Layland, J Layland, J Layland, J Tallis, JI Schwartz, JJ Lynch, JL Holtzman, JR Blinks, JS Landzberg, K Noguchi, K Sagawa, KC Vinnakota, L Batista, L Brown, L Butler, L Guo, LJ Mellors, M Eichelbaum, M Gharanei, MA Rosic, ME Conolly, MF Peters, MS Parmacek, P Bergson, R Beigel, R Josephson, R Lewis, R Seifert, R Zhang, RA Nishimura, RC Heel, RD Olson, RK Josephson, RM Bell, RS James, T Akera, T Bombardini, T Delhaas, VJ Caiozzo, W Kerns, W Semafuko, WA Catterall, Y Kihara   +56 more
core   +1 more source

Reply to Ding <i>et al.</i>: Imatinib: A Promising Therapeutic Shining Light on Pulmonary Arterial Hypertension Treatment. [PDF]

Am J Respir Crit Care Med
Rothman AMK, Villar S, Law M, Wilkins MR.   +3 more
europepmc   +1 more source