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Dose-Response Relationship of Phototherapy for Hyperbilirubinemia
Pediatrics, 2012BACKGROUND AND OBJECTIVE:Using light-emitting diodes during conventional phototherapy, it is possible to reduce the distance from light source to infant, thus increasing light irradiance. The objective of this study was to search for a “saturation point” (ie, an irradiation level above which there is no further decrease in total serum bilirubin [TsB]).
Vandborg, Pernille Kure +3 more
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The Dose-Response Relationship of Tranexamic Acid
Anesthesiology, 1995Background Prophylactic administration of the antifibrinolytic drug tranexamic acid decreases bleeding and transfusions after cardiac operations. However, the best dose of tranexamic acid for this purpose remains unknown. This study explored the dose-response relationship of tranexamic acid for hemostatic efficacy after cardiac
J C, Horrow +4 more
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Dose-Response Relationship in Radiation Leukæmia
Nature, 1959A SIGNIFICANT contribution is achieved by Drs. Armitage, Court Brown and Doll in evaluating some models postulated in assessing the leukaemogenic potency of radiations. Along this line, it appears relevant to discuss some possible interpretations of a linear dose-response, observed over a limited range of leukaemia incidence, as evidenced in the study ...
P, ARMITAGE +3 more
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Dose-response relationship for trichloroethylene in man
International Archives of Occupational and Environmental Health, 1977Twelve volunteer students were experimentally exposed to 0, 27, 81 or 201 ppm trichloroethylene for 4 hours, and suffered from irritation to mucous membrane of eyes and throat at over 27 ppm trichloroethylene. No headache or physiological responses were reported at 27 ppm; headache occurred at levels over 81 ppm.
K, Nomiyama, H, Nomiyama
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Dose-response Relationship in Angiotensin Bioassay
Cardiovascular Research, 1968In the albino rat, pressor response to 1–6 ng valine-5-angiotensin II, aspartic β-amide is a function of the logarithmic transformation of the dose of the drug. The latter transformation should be used to delineate dose-response relationship during angiotensin bioassay.
T S, Ing +3 more
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Dose-Response Relationships for Meningioma Radiosurgery
American Journal of Clinical Oncology, 2015Dose-response relationships for meningioma radiosurgery are poorly characterized. We evaluated determinants of local recurrence for meningiomas treated with Gamma Knife radiosurgery (GKRS), to guide future treatment approaches to optimize tumor control.A total of 101 consecutive patients (108 tumors) who underwent GKRS for benign, atypical, or ...
Rajni A, Sethi +9 more
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LEAD AND MORBIDITY: A DOSE-RESPONSE RELATIONSHIP
The Lancet, 1978Many laboratory tests have been recommended for monitoring factory workers exposed to lead. To select the most useful test the best predictor of selected measures of morbidity was sought. 639 lead-exposed workers in several factories were questioned about abdominal ache, constipation, and fatigue and were examined for hand tremot.
L M, Irwig +4 more
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1987
One of the most powerful tools in the analysis of toxicological events is the description of the intensity of the exposure in terms of dose, dose rate, or concentration for a specified duration of exposure in relation to the frequency or intensity of the observed responses.
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One of the most powerful tools in the analysis of toxicological events is the description of the intensity of the exposure in terms of dose, dose rate, or concentration for a specified duration of exposure in relation to the frequency or intensity of the observed responses.
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Assessment of a dose–response relationship of levetiracetam
European Journal of Neurology, 2006The aim of this study was to assess the relationship between levetiracetam dose and both efficacy and safety in adult patients with refractory partial epilepsy. Dose–response relationships for levetiracetam efficacy were evaluated using pooled data from three trials including adults with refractory partial epilepsy.
H-J, Meencke, S, Buyle
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2009
In general, the effect of a drug can be considered to be proportional to its dose; the documentation of such a relationship is important in early investigations of drug effects; effects with biological substances as e.g. interferons may go through an optimum, i.e. decreasing with increasing doses; → see also phase i.
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In general, the effect of a drug can be considered to be proportional to its dose; the documentation of such a relationship is important in early investigations of drug effects; effects with biological substances as e.g. interferons may go through an optimum, i.e. decreasing with increasing doses; → see also phase i.
openaire +1 more source