Results 151 to 160 of about 3,004,898 (219)

Robust enhanced leaf model implementation for beam-matched linear accelerators: Impact of physical leaf gap variations. [PDF]

J Appl Clin Med Phys
Lee S, Galavis PE, Jang S.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Postmenopausal Bleeding Risk after COVID-19 Vaccination: A Population-Based Self-Controlled Case Series Study. [PDF]

Yonsei Med J
Jeong NY, Park H, Cho S, Choi NK.
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Microbeam radiotherapy - clinical and dosimetric investigation of a first clinical application. [PDF]

Radiat Oncol
Kraus KM, Day LR, Wilkens JJ, Combs SE, Bartzsch S.   +4 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Commentary: Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery

Frontiers in Cardiovascular Medicine, 2017
Xiang-Dong Wu, Ke-Jia Hu, Ke-Jia Hu, Wei Huang   +3 more
doaj   +1 more source

Fine-mapping of microbeam radiation therapy-induced DNA damage in 2D cell and 3D epidermis models. [PDF]

Radiat Oncol
Nguyen M, Dombrowsky AC, Treibel F, Müller J, Raulefs S, Bartzsch S, Combs SE, Eder S, Schmid TE, Scherthan H.   +9 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Dosimetric impact of baseline shift plan in a magnetic resonance linear accelerator according to target motion and plan characteristics. [PDF]

J Appl Clin Med Phys
Tanaka S, Kadoya N, Takahashi Y, Koga S, Katsuta Y, Arai K, Hoshino T, Xiao Y, Lee W, Takahashi N, Umezawa R, Jingu K.   +11 more
europepmc   +1 more source