Results 11 to 20 of about 4,085,456 (259)

Comparative study of the efficacy of olmesartan/amlodipine vs. perindopril/amlodipine in peripheral blood pressure after missed dose in type 2 diabetes [PDF]

open access: yes, 2016
INTRODUCTION: Combination therapy is needed to control blood pressure (BP) in a large number of hypertensive patients with diabetes mellitus. Adherence to treatment is a major clinical problem; therefore, the time duration of the antihypertensive action ...
Pichler G   +3 more
core   +3 more sources

A Bayesian approach for dose-escalation in a phase I clinical trial incorporating pharmacodynamic endpoints . [PDF]

open access: yes, 2007
Bayesian decision procedures have already been proposed for and implemented in phase I dose-escalation studies in healthy volunteers. The procedures have been based on pharmacokinetic responses reflecting the concentration of the drug in blood plasma and
Hampson, Lisa   +4 more
core   +5 more sources

Balance Problems for Integer Circuits [PDF]

open access: yes, 2018
We investigate the computational complexity of balance problems for {-,*}-circuits computing finite sets of natural numbers. These problems naturally build on problems for integer expressions and integer circuits studied by Stockmeyer and Meyer (1973 ...
Dose, Titus, Titus Dose
core   +1 more source

ON THE AUTOMORPHISMS OF THE NONSPLIT CARTAN MODULAR CURVES OF PRIME LEVEL [PDF]

open access: yes, 2016
We study the automorphisms of the nonsplit Cartan modular curves Xns(p) of prime level p. We prove that if p ≥ 29 all the automorphisms preserve the cusps.
VALERIO DOSE, Dose V.
core   +1 more source

Complexity of Constraint Satisfaction Problems over Finite Subsets of Natural Numbers [PDF]

open access: yes, 2016
We study the computational complexity of constraint satisfaction problems that are based on integer expressions and algebraic circuits. On input of a finite set of variables and a finite set of constraints the question is whether the variables can be ...
Dose, Titus
core   +1 more source

P-Optimal Proof Systems for Each NP-Set but no Complete Disjoint NP-Pairs Relative to an Oracle [PDF]

open access: yes, 2019
Pudlák [P. Pudlák, 2017] lists several major conjectures from the field of proof complexity and asks for oracles that separate corresponding relativized conjectures.
Dose, Titus
core   +1 more source

Thermomechanical engineering of water-cooled plasma-facing components in fusion reactors

open access: yes, 2021
Nuclear fusion is the reaction that fuels our Sun an the other stars. Adopting fusion on Earth as an energy source for electricity production offers unique advantages, such as: virtually unlimited and widely available fuel, intrinsic safety (no chain ...
DOSE, GIACOMO
core   +1 more source

Putting directionality into context

open access: yesStellenbosch Papers in Linguistics Plus, 2014
The question of directionality, i.e. whether (simultaneous) interpreters should work only from their second into their first language or whether the opposite direction is equally acceptable or even preferable, remains controversial.
Dose, Stefanie
doaj   +1 more source

Dose calculations for [131I] meta-iodobenzylguanidine-induced bystander effects

open access: yes, 2014
Targeted radiotherapy is a potentially useful treatment for some cancers and may be potentiated by bystander effects. However, without estimation of absorbed dose, it is difficult to compare the effects with conventional external radiation treatment ...
R. J. Mairs   +17 more
core   +1 more source

Assessing directionality in context

open access: yesStellenbosch Papers in Linguistics, 2017
The directionality debate in interpreting revolves around the question of whether and how (simultaneous) interpreters’ performance differs when working from a second and into a first language compared to interpreting from a first and into a second ...
Dose, Stefanie
doaj   +1 more source

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