Results 61 to 70 of about 5,610,097 (285)

Overview of the sensitivity of Ge- and Al-doped silicon dioxide optical fibres to ionizing radiation [PDF]

open access: yes, 2012
This paper reviews the thermoluminescence sensitivity of Ge- and Al- doped SiO2 optical fibre subjected to various ionizing radiations. It is found that the Ge- doped SiO2 optical fiber has the thermoluminescence response superior to Al-doped SiO2 ...
Hashim, Suhairul   +3 more
core   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson   +20 more
wiley   +1 more source

Interaction between sphingosine and cholesteryl sulfate in epidermal lipids.

open access: yesJournal of Lipid Research, 1993
Free sphingosine, a material with multiple and potent biological activities, is known to occur in high concentration in mammalian epidermis. In the present study, thin-layer chromatography showed that in lipid extracts of human and pig stratum corneum ...
DT Downing, RW Dose, W Abraham
doaj   +1 more source

Radiation exposure from diagnostic nuclear medicine examinations in golestan province [PDF]

open access: yes, 2013
Introduction: The aim of present study was to estimate effective dose from most common procedures performed in nuclear medicine departments of Golestan province.
Asli, I.N.   +6 more
core  

The variance-covariance method: Microdosimetry in time-varying low dose-rate radiation fields [PDF]

open access: yes, 1988
The variance-covariance method is employed at low doses and in radiation fields of low dose rates from an241Am (4 nGy/s) and a90Sr (300 nGy/s) source. The preliminary applications and results illustrate some of the potential of the method, and show that ...
Breckow, Joachim   +3 more
core   +1 more source

Alveolar Soft Part Sarcoma in Pediatric and Young Adult Patients: A Report From the Children's Oncology Group Study ARST0332

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane   +11 more
wiley   +1 more source

PB2130: RATIONAL FOR METHOTREXATE USAGE FOR THE TREATMENT AND PREVENTION OF CNS INVOLVEMENT IN PATIENTS WITH HIGH-GRADE B-CELL LYMPHOMAS.

open access: yesHemaSphere, 2022
A. Misyurina   +6 more
doaj   +1 more source

A phase I pharmacokinetic and pharmacodynamic study of the oral mitogen-activated protein kinase kinase (MEK) inhibitor, WX-554, in patients with advanced solid tumours [PDF]

open access: yes, 2016
Purpose: We performed a multi-centre phase I study to assess the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of the orally available small molecule mitogen-activated protein kinase kinase (MEK) 1/2 inhibitor, WX-554, and to determine the ...
Allen, Rodger   +21 more
core   +2 more sources

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano   +7 more
wiley   +1 more source

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba   +11 more
wiley   +1 more source

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