Results 131 to 140 of about 1,766,452 (265)

Ultra-high dose rate electron FLASH beam irradiation using a modified clinical linear accelerator. [PDF]

PLoS One
Cho GS, Kim KT, Lee SS, Kim JH, Lee DH, Chang HS, Choi SH, Kim KB, Yang TK, An DH, Kim GB, Kang KU, Kang JK, Kim EJ, Paik EK, Kim MS, Jang WI, Yang KM.   +17 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

High-dose-rate brachytherapy for eyelid carcinoma: Implant technique and review. [PDF]

J Contemp Brachytherapy
Guinot JL, Gutierrez C, Vercher M, Juárez M, Santos MA, Núñez M, Canos S, Slocker A, Najjari D.   +8 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Experimental characterization of proton minibeam therapy delivery under FLASH dose-rate conditions. [PDF]

Sci Rep
Lin Y, Wu W, Setianegara J, Wang A, Gerard N, Nys J, Gan GN, Gao H.   +7 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Secondary primary tumors following iodine-125 low-dose-rate brachytherapy for localized prostate cancer. [PDF]

Int J Clin Oncol
Niwa K, Iinuma K, Nakano M, Tomioka M, Ito M, Mori T, Kawase K, Taniguchi T, Tobisawa Y, Nakane K, Matsuo M, Koie T.   +11 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Combined High Dose-Rate Interstitial Brachytherapy and Stereotactic Body Radiotherapy in Unresectable Primary Vaginal Melanoma: A Case Report. [PDF]

Cureus
Ariani RT, Khan S, Venkat P.
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source