Results 161 to 170 of about 1,766,452 (265)

Development and application of <i>in-vivo</i> dose and time-resolved measurements for clinical application of ultra-high dose rate radiotherapy. [PDF]

Phys Imaging Radiat Oncol
Dal Bello R, Psoroulas S, Flückiger D, Krayenbühl J, Kemper A, Kranzer R, Côté B, von der Grün J, Balermpas P, Guckenberger M, Tanadini-Lang S.   +10 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

The First Moroccan Experience of Personalized Template‑Guided High-Dose-Rate Brachytherapy for Organ Preservation in Glans Squamous Cell Carcinoma: Game Changer or Challenge? [PDF]

Cureus
Samlali H, Assaid N, Khobbaizi Y, Samlali R, Jouhadi H.   +4 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Risk of mortality from diseases of the circulatory system due to occupational chronic radiation exposure, considering the radiation dose rate. [PDF]

Sci Rep
Azizova T, Grigoryeva E, Hamada N.
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Is Ultrahigh Dose Rate Critical for the Effectiveness of Microbeam Radiation Therapy in a Broad-Beam Combined Treatment? [PDF]

Adv Radiat Oncol
Engels E, Forrester HB, Trappetti V, Mouchemore K, Klein M, Sprung AH, Brunt K, Barnes MJ, Cameron M, de Rover V, Dietler BB, Rosenfeld AB, Lerch MLF, Anderson RL, Martin OA, Djonov VG.   +15 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Development and characterization of a prototype selenium-75 high dose rate brachytherapy source. [PDF]

Med Phys
Kalinowski J, Tal O, Reid J, Munro J, Moran M, Armstrong A, Enger SA.   +6 more
europepmc   +1 more source