Results 1 to 10 of about 827,349 (150)

Dosimetric Comparison of IMRT with 3D-CRT Regarding Their Contribution to the Treatment Plan Optimization Using Rando Phantom with a Realistic Lung Cancer Radiotherapy Treatment Planning [PDF]

Iranian Journal of Medical Physics, 2021
Introduction: This study compared a three-dimensional conformal radiation therapy (3D-CRT) with a recently implemented intensity modulation radiation therapy (IMRT) technique performed in the irradiation of lung cancer.
Karim Benkahila, Faycal Kharfi, Fouad Boulakhssaim, Saad Khoudri   +3 more
doaj   +1 more source

Validation of the spectrophotometric method for the dosing of some combined capsules [PDF]

The Moldovan Medical Journal, 2021
Background: UV-Vis spectrophotometry remains the most accessible spectral method with a high degree of sensitivity and information. The advantage of the method consists in its universality, the ability to combine with other methods, the minimum error, as
Livia Uncu, Vladilena Evtodienco, Ecaterina Mazur, Elena Donici, Vladimir Valica   +4 more
doaj   +1 more source

Sorting Out the Risks and Benefits of the #797 Recommended Intrapartum Vancomycin Dosing Approach

Antibiotics, 2022
ACOG Committee Opinion #797 proposed intrapartum vancomycin dosing guidelines in the absence of thorough evaluation of its risk versus benefit profile on the maternal and neonatal systems.
Andras Farkas, Arsheena Yassin
doaj   +1 more source

β-Lactam Pharmacokinetic/Pharmacodynamic Target Attainment in Intensive Care Unit Patients: A Prospective, Observational, Cohort Study

Antibiotics, 2023
Background: The aims of this study were to describe pharmacokinetic/pharmacodynamic target attainment in intensive care unit (ICU) patients treated with continuously infused ß-lactam antibiotics, their associated covariates, and the impact of dosage ...
Romain Guilhaumou, Constance Chevrier, Jean Loup Setti, Elisabeth Jouve, Amélie Marsot, Nathan Julian, Olivier Blin, Pierre Simeone, David Lagier, Djamel Mokart, Nicolas Bruder, Marc Garnier, Lionel Velly   +12 more
doaj   +1 more source

Standard and increased canakinumab dosing to quiet macrophage activation syndrome in children with systemic juvenile idiopathic arthritis

Frontiers in Pediatrics, 2022
ObjectiveMacrophage activation syndrome (MAS) is a life-threatening, potentially fatal condition associated with systemic juvenile idiopathic arthritis (sJIA). Interleukin-1 (IL-1) is a key cytokine in the pathogenesis of sJIA MAS.
Mikhail M. Kostik, Eugenia A. Isupova, Konstantin Belozerov, Tatyana S. Likhacheva, Evgeny N. Suspitsin, Evgeny N. Suspitsin, Evgeny N. Suspitsin, Rinat Raupov, Vera V. Masalova, Irina A. Chikova, Margarita F. Dubko, Olga V. Kalashnikova, Vyacheslav G. Chasnyk, Randy Q. Cron   +13 more
doaj   +1 more source

PROVE: Retrospective, non‐interventional, Phase IV study of perampanel in real‐world clinical care of patients with epilepsy

Epilepsia Open, 2022
Objective To assess retention, dosing, efficacy, and safety of perampanel in a large cohort of patients with epilepsy during routine clinical care. Methods PROVE was a retrospective, non‐interventional Phase IV study (NCT03208660).
Robert T. Wechsler, James Wheless, Muhammad Zafar, Graham R. Huesmann, Marcelo Lancman, Eric Segal, Michael Chez, Sami Aboumatar, Anna Patten, Alejandro Salah, Manoj Malhotra   +10 more
doaj   +1 more source

Evaluation of age-based local anaesthetic dosing of bupivacaine for popliteal sciatic nerve block in children undergoing foot and ankle surgery: A prospective single arm interventional study

Indian Journal of Anaesthesia, 2023
Background and Aims: Recommendations on paediatric single-injection local anaesthetic (LA) dosing for peripheral nerve blocks (PNBs) are based on the children's weight and limited by weight-based toxicity concerns.
Srinivasan Parthasarathy, T Kumar Venkatesh, Balachandar Saravanan   +2 more
doaj   +1 more source

Population Pharmacokinetics and Dosing Regimen Optimization of Latamoxef in Chinese Children

Pharmaceutics, 2022
The present study aimed to establish population pharmacokinetic models of latamoxef, as well as its R- and S-epimers, and generate findings to guide the individualized administration of latamoxef in pediatric patients. A total of 145 in-hospital children
Yang Wang, Dan Sun, Yan Mei, Sanlan Wu, Xinlin Li, Sichan Li, Jun Wang, Liuliu Gao, Hua Xu, Yali Tuo   +9 more
doaj   +1 more source

Optimising Vaccine Dose in Inoculation against SARS-CoV-2, a Multi-Factor Optimisation Modelling Study to Maximise Vaccine Safety and Efficacy

Vaccines, 2021
Developing a vaccine against the global pandemic SARS-CoV-2 is a critical area of active research. Modelling can be used to identify optimal vaccine dosing; maximising vaccine efficacy and safety and minimising cost.
John Benest, Sophie Rhodes, Matthew Quaife, Thomas G. Evans, Richard G. White   +4 more
doaj   +1 more source

Population Pharmacokinetics of Caspofungin and Dosing Optimization in Children With Allogeneic Hematopoietic Stem Cell Transplantation

Frontiers in Pharmacology, 2020
Caspofungin is the first echinocandin antifungal agent that licented for pediatric use in invasive candidiasis and aspergillosis. In this study, we evaluated the population pharmacokinetics of caspofungin and investigate appropriate dosing optimization ...
Chang-He Niu, Hua Xu, Liu-Liu Gao, Ying-Ming Nie, Li-Peng Xing, Li-Peng Yu, San-Lan Wu, Yang Wang   +7 more
doaj   +1 more source