Results 91 to 100 of about 3,798,723 (244)

Tildrakizumab in the treatment of psoriasis: latest evidence and place in therapy. [PDF]

open access: yes, 2019
Psoriasis is a chronic inflammatory disorder that is clinically characterized by scaly cutaneous plaques. New evidence suggests that dysregulation of interleukin (IL)-23, a key cytokine in the T-helper-17 pathway, plays a vital role in the development of
Lee, Erica B   +4 more
core  

Clinical Pharmacokinetics and Pharmacodynamics of Pazopanib: Towards Optimized Dosing

open access: yesClinical Pharmacokinetics, 2017
Pazopanib is an inhibitor of the vascular endothelial growth factor receptor, platelet-derived growth factor receptor, fibroblast growth factor receptor and stem cell receptor c-Kit, and has been approved for the treatment of renal cell carcinoma and ...
R. Verheijen   +4 more
semanticscholar   +1 more source

A randomized trial to determine the impact on compliance of a psychophysical peripheral cue based on the Elaboration Likelihood Model [PDF]

open access: yes, 2008
Objective: Non-compliance in clinical studies is a significant issue, but causes remain unclear. Utilizing the Elaboration Likelihood Model of persuasion, this study assessed the psychophysical peripheral cue ‘Interactive Voice Response System (IVRS ...
Abu-Hasaballah   +33 more
core   +1 more source

Development of the laboratory anaerobic bioreactor for wet and dry digestion processes [PDF]

open access: yes, 2016
This article presents partial results of the laboratory development of an anaerobic bioreactor designed for the physical modelling of (semi)continuous dry or wet anaerobic digestion processes.
Chamrádová, Kateřina   +2 more
core  

Artemisinins [PDF]

open access: yes, 2005
Artemisinins were discovered to be highly effective antimalarial drugs shortly after the isolation of the parent artemisinin in 1971 in China. These compounds combine potent, rapid antimalarial activity with a wide therapeutic index and an absence of ...
Haynes, RK, Krishna, S, Woodrow, CJ
core   +3 more sources

A meta‐analysis of toxicities related to hydroxycarbamide dosing strategies

open access: yeseJHaem, 2020
Due to fear of short‐term toxicities, there is nonconsensus of hydroxycarbamide dosing strategy (escalated vs fixed‐dosing methods), which contributes to its suboptimal use.
Joacy G. Mathias   +9 more
doaj   +1 more source

Gut Microbiota and Tacrolimus Dosing in Kidney Transplantation

open access: yesPLoS ONE, 2015
Tacrolimus dosing to establish therapeutic levels in recipients of organ transplants is a challenging task because of much interpatient and intrapatient variability in drug absorption, metabolism, and disposition.
J. Lee   +8 more
semanticscholar   +1 more source

Efficacy of low dose pirfenidone in idiopathic pulmonary fibrosis: real world experience from a tertiary university hospital [PDF]

open access: gold, 2020
Myung Jin Song   +11 more
openalex   +1 more source

Towards the fabrication of phosphorus qubits for a silicon quantum computer

open access: yes, 2001
The quest to build a quantum computer has been inspired by the recognition of the formidable computational power such a device could offer. In particular silicon-based proposals, using the nuclear or electron spin of dopants as qubits, are attractive due
A. S. Dzurak   +38 more
core   +1 more source

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