Tildrakizumab in the treatment of psoriasis: latest evidence and place in therapy. [PDF]
Psoriasis is a chronic inflammatory disorder that is clinically characterized by scaly cutaneous plaques. New evidence suggests that dysregulation of interleukin (IL)-23, a key cytokine in the T-helper-17 pathway, plays a vital role in the development of
Lee, Erica B +4 more
core
Clinical Pharmacokinetics and Pharmacodynamics of Pazopanib: Towards Optimized Dosing
Pazopanib is an inhibitor of the vascular endothelial growth factor receptor, platelet-derived growth factor receptor, fibroblast growth factor receptor and stem cell receptor c-Kit, and has been approved for the treatment of renal cell carcinoma and ...
R. Verheijen +4 more
semanticscholar +1 more source
A randomized trial to determine the impact on compliance of a psychophysical peripheral cue based on the Elaboration Likelihood Model [PDF]
Objective: Non-compliance in clinical studies is a significant issue, but causes remain unclear. Utilizing the Elaboration Likelihood Model of persuasion, this study assessed the psychophysical peripheral cue ‘Interactive Voice Response System (IVRS ...
Abu-Hasaballah +33 more
core +1 more source
Development of the laboratory anaerobic bioreactor for wet and dry digestion processes [PDF]
This article presents partial results of the laboratory development of an anaerobic bioreactor designed for the physical modelling of (semi)continuous dry or wet anaerobic digestion processes.
Chamrádová, Kateřina +2 more
core
Artemisinins were discovered to be highly effective antimalarial drugs shortly after the isolation of the parent artemisinin in 1971 in China. These compounds combine potent, rapid antimalarial activity with a wide therapeutic index and an absence of ...
Haynes, RK, Krishna, S, Woodrow, CJ
core +3 more sources
A meta‐analysis of toxicities related to hydroxycarbamide dosing strategies
Due to fear of short‐term toxicities, there is nonconsensus of hydroxycarbamide dosing strategy (escalated vs fixed‐dosing methods), which contributes to its suboptimal use.
Joacy G. Mathias +9 more
doaj +1 more source
Effects of low chronic doses of ionizing radiation on antioxidant enzymes and G6PDH activities in Stipa capillata (Poaceae) [PDF]
R. Zaka
openalex +1 more source
Gut Microbiota and Tacrolimus Dosing in Kidney Transplantation
Tacrolimus dosing to establish therapeutic levels in recipients of organ transplants is a challenging task because of much interpatient and intrapatient variability in drug absorption, metabolism, and disposition.
J. Lee +8 more
semanticscholar +1 more source
Efficacy of low dose pirfenidone in idiopathic pulmonary fibrosis: real world experience from a tertiary university hospital [PDF]
Myung Jin Song +11 more
openalex +1 more source
Towards the fabrication of phosphorus qubits for a silicon quantum computer
The quest to build a quantum computer has been inspired by the recognition of the formidable computational power such a device could offer. In particular silicon-based proposals, using the nuclear or electron spin of dopants as qubits, are attractive due
A. S. Dzurak +38 more
core +1 more source

