Results 121 to 130 of about 1,146,644 (343)

Specific circulating microRNAs display dose-dependent responses to variable intensity and duration of endurance exercise [PDF]

, 2018
A. Ramos, Claire Lo, Leonard E. Estephan, Yi-Yin Tai, Ying Tang, Jingsi Zhao, Masataka Sugahara, John Gorcsan, Marcel G. Brown, Daniel E. Lieberman, Stephen Y. Chan, Aaron L. Baggish   +11 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Factors associated with elevated gentamicin trough levels in neonates: a retrospective analysis of dosing and clinical parameters

Frontiers in Pediatrics
ObjectiveInvestigate determinants of elevated gentamicin trough levels in neonates.MethodsThis single-center retrospective analysis used a multivariate linear regression model to explore the relationship between gentamicin trough concentrations and ...
Julian Trah, Julian Trah, Philipp Deindl, Alexandra Luister, Claudia Langebrake, Dominique Singer, Chinedu Ulrich Ebenebe   +6 more
doaj   +1 more source

Electrostatic Switching for Spatiotemporal Dose Control in a Transmission Electron Microscope [PDF]

, 2022
Bryan W. Reed, R S Bloom, G Eyzaguirre, C Henrichs, A A Moghadam, D J Masiel   +5 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Targeted therapy with a localised abluminal groove, low-dose sirolimus-eluting, biodegradable-polymer coronary stent – five-year results of the TARGET All Comers randomised clinical trial [PDF]

, 2023
Alexandra J. Lansky, Bo Xu, Andreas Baumbach, Henning Kelbæk, Niels van Royen, Ming Zheng, Paul Knaapen, Ton Slagboom, Tom Johnson, Georgios J. Vlachojannis, Karin Arkenbout, Lene Holmvang, Luc Janssens, Salvatore Brugaletta, Christoph Naber, Thomas Schmitz, Richard Anderson, Harald Rittger, Sérgio Berti, Emanuele Barbato, Gábor G. Tóth, Luc Maillard, Christian Valina, Paweł Buszman, Hölger Thiele, Volker Schächinger, William Wijns   +26 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Therapeutic effect of local administration of low-dose simvastatin-conjugated gelatin hydrogel for fracture healing [PDF]

, 2012
Tomoaki Fukui, Masaaki Ii, Taro Shoji, Tomoyuki Matsumoto, Yutaka Mifune, Yohei Kawakami, Hiroshi Akimaru, Atsuhiko Kawamoto, Tomoya Kuroda, Takashi Saito, Yasuhiko Tabata, Ryosuke Kuroda, Masahiro Kurosaka, Takayuki Asahara   +13 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Safe use of Dexamethasone in pediatrics: design and evaluation of a novel stable oral suspension

Pharmaceutical Technology in Hospital Pharmacy, 2018
Dexamethasone is used in pediatrics mainly for treatment of croup and bronchopulmonary dysplasia. Commercially available pediatric oral formulations include inadequate excipients for this population. When there are only commercially available oral dosage
Santoveña-Estévez Ana, Dorta-Vera Diego, González-García Iris, Suárez-González Javier, Teigell-Pérez Nuria, Fariña José B   +5 more
doaj   +1 more source