Results 21 to 30 of about 1,146,644 (343)

Optimizing Guideline-Recommended Antibiotic Doses for Pediatric Infective Endocarditis [PDF]

open access: yes, 2016
The American Heart Association recently published an updated scientific statement on the management of infective endocarditis in childhood. The recommendations included for vancomycin, aminoglycoside, and β-lactam dosing and monitoring are based ...
Israel, Emily N.   +3 more
core   +3 more sources

Vibration-Assisted Handling of Dry Fine Powders

open access: yesActuators, 2018
Since fine powders tend strongly to adhesion and agglomeration, their processing with conventional methods is difficult or impossible. Typically, in order to enable the handling of fine powders, chemicals are added to increase the flowability and reduce ...
Paul Dunst   +3 more
doaj   +1 more source

β-Lactam Pharmacokinetic/Pharmacodynamic Target Attainment in Intensive Care Unit Patients: A Prospective, Observational, Cohort Study

open access: yesAntibiotics, 2023
Background: The aims of this study were to describe pharmacokinetic/pharmacodynamic target attainment in intensive care unit (ICU) patients treated with continuously infused ß-lactam antibiotics, their associated covariates, and the impact of dosage ...
Romain Guilhaumou   +12 more
doaj   +1 more source

MTN-001: Randomized Pharmacokinetic Cross-Over Study Comparing Tenofovir Vaginal Gel and Oral Tablets in Vaginal Tissue and Other Compartments [PDF]

open access: yes, 2013
Background: Oral and vaginal preparations of tenofovir as pre-exposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) infection have demonstrated variable efficacy in men and women prompting assessment of variation in drug concentration as an ...
A Pruvost   +39 more
core   +5 more sources

Clinical Effectiveness and Dose Titration in Pediatric Practice

open access: yesZdorovʹe Rebenka, 2016
The paper is devoted to the questions of usage of one of the popular antipyretic and anesthetic drug in pediatric practice — ibuprofen. In the article there are generalized literature data and own experience in ibuprofen dose titration in single dose 5 ...
Yu.V. Marushko   +2 more
doaj   +1 more source

Burosumab therapy in children with x-linked hypophosphatemia [PDF]

open access: yes, 2018
BACKGROUND X-linked hypophosphatemia is characterized by increased secretion of fibroblast growth factor 23 (FGF-23), which leads to hypophosphatemia and consequently rickets, osteomalacia, and skeletal deformities.
Boot, Annemieke M   +13 more
core   +2 more sources

Population Pharmacokinetics of Caspofungin and Dosing Optimization in Children With Allogeneic Hematopoietic Stem Cell Transplantation

open access: yesFrontiers in Pharmacology, 2020
Caspofungin is the first echinocandin antifungal agent that licented for pediatric use in invasive candidiasis and aspergillosis. In this study, we evaluated the population pharmacokinetics of caspofungin and investigate appropriate dosing optimization ...
Chang-He Niu   +7 more
doaj   +1 more source

Effect of Enfortumab Vedotin Dose Adjustment on Efficacy in Metastatic Urothelial Carcinoma: A Retrospective Single-Center Experience 

open access: yesCancer Management and Research, 2023
Anna Clennon,1 Megan Hinkley,1 Kristen Nymberg,1 Lauren Ledbetter,1 Demond Handley,2 Eric McLaughlin,2 Amir Mortazavi,3 Katharine A Collier3 1Department of Pharmacy, the James Cancer Hospital at the Ohio State University, Columbus, OH, USA; 2Department ...
Clennon A   +7 more
doaj  

The Management of Glucocorticoid Therapy in Liver Failure

open access: yesFrontiers in Immunology, 2019
Liver failure is characterized by rapid progression and high mortality. Excessive systemic inflammation is considered as the trigger of liver failure. Glucocorticoids (GCs) can rapidly suppress excessive inflammatory reactions and immune response.
Ran Xue, Ran Xue, Qinghua Meng
doaj   +1 more source

Pharmacogenomic testing and its future in community pharmacy [PDF]

open access: yes, 2020
Although it is common to see pharmacogenomic testing used North America and Australia, it is not yet part of practice in the UK. With the promise of genomic screening becoming part of the NHS, pharmacists must equip themselves with a knowledge of how the
Wright, David, Youssef, Essra
core   +1 more source

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