Results 81 to 90 of about 97,738 (257)

Improved Reliability of Dot Probe Measures with Response-Based Computation: An Application with Young Violence-Exposed Children. [PDF]

Cognit Ther Res, 2023
Loomis AM, Evans TC, Grasso DJ, Briggs-Gowan M.   +3 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Delivering Quantum Dot Probes into the Cytosol [PDF]

Cancer Discovery, 2012
Abstract Fluorescent nanoparticles packaged with antibodies inside virus-based liposomes can identify EGFR proteins within brain tumor cells.
openaire   +1 more source

Synthesis, Microstructure, Optical Properties, and Sensitive Amoxicillin Detection of Carbon Dots

Indonesian Journal of Chemical Research
The detection of amoxicillin has been successfully carried out using C-dot fluorescence probes made from d-glucose and urea.  The fluorescence probe has an intense bright blue emission under UV light at 395 nm and and depends on the excitation and ...
Yuni Aldriani Lubis, Saharman Gea, Muhammad Frassetia Lubis, Woei Wu Larry Pai, Marpongahtun Marpongahtun   +4 more
doaj   +1 more source

Erratum: Attentional capture by fearful faces requires consciousness and is modulated by task-relevancy: a dot-probe EEG study. [PDF]

Front Neurosci, 2023
Frontiers Production Office.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A single-electron probe for buried optically active quantum dot

AIP Advances, 2012
We present a simple method that enables both single electron transport through a self-assembled quantum dot and photon emission from the dot. The quantum dot buried in a semiconductor matrix is electrically connected with nanogap electrodes through ...
T. Nakaoka, K. Watanabe, N. Kumagai, Y. Arakawa   +3 more
doaj   +1 more source

Reliability of attention bias and attention bias variability to climate change images in the dot-probe task. [PDF]

Front Psychol, 2022
Carlson JM, Fang L, Coughtry-Carpenter C, Foley J.   +3 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source