Introducing a novel sham acupuncture method for double-blind trials: A validation study
Introduction: Various clinical studies have been conducted worldwide to evaluate the effectiveness of acupuncture; however, designing an adequate control group is challenging.
Sung Min Lim+4 more
doaj +3 more sources
TOLERANCE TEST ON EMBAY 8440 (PRAZIQUANTEL) FOR SCHISTOSOMIASIS JAPONICA BY DOUBLE BLIND METHOD
A newly developed anti-schistosomal drug, EMBAY 8440 (Praziquantel), by E. Merck and Bayer A. G., a marked characteristic of which consisted in the only one day administration per os, needed a tolerance test to know the side-effect in patients of schistosomiasis japonica by double blind method.By treating these patients with 20 mg/kg dose, side-effects
Etsuji Kamo, Tatsushi Ishizaki
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Clinical and biochemical assessments of damage due to perinatal asphyxia: a double blind trial of a quantitative method. [PDF]
Using conventional criteria, a series of 26 infants was selected for intrapartum asphyxia from about 4000 deliveries over one year at a single hospital to assess the efficacy of a new biochemical method. Tissue damage was estimated from urinary excretion of hypoxanthine, an important and central intermediate in purine metabolism.
Ian Laing, J. K. Brown, R. A. Harkness
openalex +5 more sources
Methods of defining the non-inferiority margin in randomized, double-blind controlled trials: a systematic review [PDF]
There is no consensus on the preferred method for defining the non-inferiority margin in non-inferiority trials, and previous studies showed that the rationale for its choice is often not reported. This study investigated how the non-inferiority margin is defined in the published literature, and whether its reporting has changed over time.A systematic ...
Turki A. Althunian+4 more
openalex +6 more sources
Double-Sided Fabrication of Low-Leakage-Current Through-Silicon Vias (TSVs) with High-Step-Coverage Liner/Barrier Layers [PDF]
In this paper, a novel through-silicon via (TSV) fabrication strategy based on through-hole structures is proposed for low-cost and low-complexity manufacturing. Compared to conventional TSV fabrication processes, this method significantly simplifies the
Baoyan Yang+3 more
doaj +2 more sources
Allocation Concealment Methods of Alternative Vaccines in Double-blinded Vaccine Plants and Foods Trials [PDF]
In this study, specific steps are described of concealment allocation methods in double-blinded vaccine plants and foods trials. What is more, comparison among them is also conducted. Damage of injected vaccines during the transportation and storage is common which affects the food vaccination program in plants and foods trials.
Yujia Kong, Jielai Xia, Ling Wang
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Background: Tranexamic acid (TXA) is an antifibrinolytic agent with promising benefits in facial rejuvenation surgery. The best way to administer this medication for therapeutic value is currently unknown. This study compared outcomes for facelift patients given TXA intravenously versus locally in tumescent solution.
Steven P. Davison+4 more
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CLINICAL EVALUATION OF DRUG EFTICACY BY THE DOUBLE BLIND METHOD IN MEDICINE
N Shimizu
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A double-blind pilot randomized controlled trial of topical tranexamic acid after sinus surgery [PDF]
Background: There has been limited study of topical tranexamic acid (TXA) in endoscopic sinus surgery (ESS). We report a pilot study, examining the effects of topical TXA with regards to recovery after ESS.
A.R. Kumar, A.J. Wood
doaj +1 more source