Results 141 to 150 of about 1,459,434 (319)

Supplemental Methods and Materials from A Phase IIa Randomized, Double-Blind Trial of Erlotinib in Inhibiting Epidermal Growth Factor Receptor Signaling in Aberrant Crypt Foci of the Colorectum

, 2023
Daniel L. Gillen, Frank L. Meyskens, Timothy R. Morgan, Jason A. Zell, Robert Carroll, Richard V. Benya, Wen‐Pin Chen, Allen Mo, Chris Tucker, Asmita Bhattacharya, Zhiliang Huang, Myra Arcilla, Vanessa Nl Wong, Jinah Chung, Rachel Gonzalez, Luz M. Rodriguez, Éva Szabó, Daniel W. Rosenberg, Steven M. Lipkin   +18 more
openalex   +1 more source

Low‐Irradiance Antimicrobial Blue Light‐Bathing Therapy for Wound Infection Control

Advanced Science, EarlyView.
Antimicrobial blue light has been shown as an appealing non‐pharmacological antimicrobial alternative. However, its clinical applications have been hindered by high irradiance‐associated photothermal risks. In this work, a low‐irradiance blue light‐bathing concept and a wearable photonic wound patch are established to address this challenge in terms of
Jie Hui, Wonjoon Moon, Pu‐Ting Dong, Carolina dos Anjos, Laisa Negri, Hao Yan, Ying Wang, Joshua Tam, Tianhong Dai, R. Rox Anderson, Jeremy Goverman, Jeffrey A. Gelfand, Seok‐Hyun Yun   +12 more
wiley   +1 more source

On the acceleration of gradient methods: the triangle steepest descent method [PDF]

arXiv
The gradient type of methods has been a competitive choice in solving large scale problems arising from various applications such as machine learning. However, there is still space to accelerate the gradient methods. To this end, in this paper, we pay attention to the cyclic steepest descent method (CSD), and prove that the CSD method has a gradient ...
arxiv  

A Comparison of Tranexamic Acid Administration Methods on Intraoperative and Postoperative Outcomes in Elective Rhytidectomies: A Randomized, Double-Blind Study

, 2023
Hrijeeta Mukherjee, Molly Ellor, Sushma Shankar, Steven P. Davison   +3 more
openalex   +1 more source

Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis

Advanced Science, EarlyView.
Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao, Qirong Xie, Qiang Zheng, Jingping Zhang, Mengyu Yao, Zhongyong Du, Lujun Zhang, Tianyang Hu, Yunli Zhao, Jianlin Du, Yongyong Li, Yuxing Feng, ND Melgiri, Xiaodong Zhao, Rongzhong Huang, Yang Sun   +15 more
wiley   +1 more source

Clinical studies on infectious disease of dental origin after administration of Neuzym, especially by the double blind method in combination with the use of Neomyson

, 1972
Keigo KUDO, Yukio FUJIOKA, Yasushi Ohashi, S Seki, Hayato ENDO, Moriaki Inawashiro, Teruo SHIBATA, Mitugi HIRAGA, Masataka Yoshida, Nobuaki Suzuki, Koichi Fukuda, Naoyuki Komoribayashi   +11 more
openalex   +2 more sources

Gut Microbiota Modulation by Inulin Improves Metabolism and Ovarian Function in Polycystic Ovary Syndrome

Advanced Science, EarlyView.
This work proposes a novel strategy targeting gut microbiota for managing polycystic ovary syndrome (PCOS). Inulin, a gut microbiota modulator, notably boosts the growth of short‐chain fatty acids (SCFAs)‐producers, represented by Bifidobacterium, thereby improving glucolipid metabolism and ovarian function of PCOS through suppressing the inflammatory ...
Lulu Geng, Xin Yang, Jiani Sun, Ximing Ran, Dan Zhou, Mingming Ye, Li Wen, Ruirui Wang, Miaoxin Chen   +8 more
wiley   +1 more source

Feasibility of blinding spinal manual therapy interventions among participants and outcome assessors: protocol for a blinding feasibility trial

Pilot and Feasibility Studies
Introduction Blinding is a methodologically important aspect in randomised controlled trials yet frequently overlooked in trials of spinal manual therapy interventions for back pain.
Javier Muñoz Laguna, Astrid Kurmann, Léonie Hofstetter, Emanuela Nyantakyi, Lauren Clack, Heejung Bang, Nadine E. Foster, Julia Braun, Milo A. Puhan, Mazda Farshad, Cesar A. Hincapié   +10 more
doaj   +1 more source

Kanendomycin Treatment on Bacillary Dysentery and its Allied Disorders-with Special Reference to the Comparison with Kanamycin by Double Blind Method

, 1973
Shigehiko SUGIYAMA, Mitsuru AKAO, Toshio Kobayashi, Chihiro Imai, Takuzo YAMAMOTO, Okisuke TSUNODA   +5 more
openalex   +2 more sources

Depletion of Hepatic SREBP2 Protects Against Hypercholesterolemia and Atherosclerosis through the ANGPTL3‐LPL Axis

Advanced Science, EarlyView.
This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang, Jia You Sarafina Choe, Yu Shi, Thi Tun Thi, Xiaoyun Cao, Yang Hu, Kai Yan Cheng, Hui Li, Yang Ji, Yan Liu, Matthew Ackers‐Johnson, Roger S.Y. Foo, Yujia Shen, Haojie Yu   +13 more
wiley   +1 more source