Results 231 to 240 of about 1,630,882 (368)

Identification and Drug Screening of Single Cells from Human Tumors on Semiconductor Chip for Cancer Precision Medicine

open access: yesAdvanced Science, EarlyView.
The study innovatively integrates single‐cell electric impedance identification and drug screening on a semiconductor chip, addressing tumor heterogeneity limitations. The system achieves label‐free cancer cell recognition while concurrently evaluating drug efficacy on cancer cells and toxicity on noncancerous cells.
Wenhao Hui   +13 more
wiley   +1 more source

Self‐Powered UV Dual‐Band Photodetector Based on Cs3BiCl6/GaN Heterojunction for Logical Operation and Encrypted Photo‐Communication

open access: yesAdvanced Science, EarlyView.
Utilizing the special dual‐band absorption characteristics of Cs3BiCl6 and its strong surface‐charge recombination behavior, a self‐powered UV dual‐band photodetector based on Cs3BiCl6/GaN heterojunction is developed. As a result, the photodetector exhibits excellent specific detectivity of 1.23 × 1012 Jones and ultrafast response speed of τr/τf = 28 ...
Jingli Ma   +11 more
wiley   +1 more source

PP2A Promotes the Symmetric Division of MUC1‐Dominant Cancer Stem‐Like Cells in Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
During the G2/M phase, mucin1 (MUC1) activates protein phosphatase 2A (PP2A), leading to reduced phosphorylation of protein kinase C ζ (PKCζ) and NUMB, which promotes symmetric division and expansion of cancer stem‐like cells (CSLCs), thereby driving tumorigenesis. Combined inhibition of the MUC1–PP2A axis using LB100/GO203 with etoposide restores PKCζ
Shengze Li   +15 more
wiley   +1 more source

Intraoperative Fast Adaptive Focus Tracking Robotic OCT Enables Real‐Time Tumor Grading and Large‐Area Microvascular Imaging in Human Spinal Cord Surgery

open access: yesAdvanced Science, EarlyView.
The fast adaptive focus tracking robotic optical coherence tomography (FACT‐ROCT) offers real‐time, high‐resolution imaging of spinal cord tumors during surgery. By reducing motion artifacts with robotics and adaptive focal tracking, it accurately differentiates tumor grades using a novel attenuation coefficient marker and reveals critical ...
Bin He   +16 more
wiley   +1 more source

The Development of Publications on Catheter-Related Bladder Discomfort: A Bibliometric Analysis. [PDF]

open access: yesTher Clin Risk Manag
Jiang W   +6 more
europepmc   +1 more source

Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation

open access: yesAdvanced Science, EarlyView.
The engineered calprotectin biosensor detects gut inflammation, processes the signal through genetic regulation, and responds by expressing the reporter sfGFP and the therapeutic protein secIL10. This dual functionality enables the engineered biosensor not only to sense but also to mitigate gut inflammation, highlighting its potential for disease ...
Duolong Zhu   +8 more
wiley   +1 more source

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